Results 21 to 30 of about 76,985,047 (293)
Investigation of Interleukin-7 Serum Levels in Patients with Osteosarcoma [PDF]
Primary bone cancers, mainly osteosarcoma, are the most common malignancies in human musculoskeletal system. Several risk factors including inflammatory and immunologic factors have been introduced in this disease of which cytokines can be named. The aim
Hamed Fouladseresht +3 more
doaj +1 more source
Interleukin-7 (IL-7) is a cytokine essential for cell development, proliferation and survival. However, its role in oocyte maturation is largely unknown.
Dongjin Oh +9 more
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Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring [PDF]
Background Breastfeeding protects against illnesses and death in hazardous environments, an effect partly mediated by improved immune function. One hypothesis suggests that factors within milk supplement the inadequate immune response of the offspring,
Andrew M Prentice +11 more
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Following acute stress such as trauma or sepsis, most of critically ill elderly patients become immunosuppressed and susceptible to secondary infections and enhanced mortality.
Chrystel Marton +11 more
doaj +1 more source
BackgroundChimeric antigen receptor T (CAR-T) cell therapy has made significant advances for hematological malignancies but encounters obstacles in the treatment of solid tumors mainly due to tumor immunosuppressive microenvironment ...
Fanfan Li +15 more
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Characterization of lymphoid tissue inducer cells and lymphoid tissue development in adult interleukin 7 transgenic mice [PDF]
During embryogenesis, the development of secondary lymphoid organs (SLOs) such as lymph nodes (LNs) and Peyer’s patches (PPs) requires the cellular crosstalk between vascular cell adhesion molecule (VCAM)-1+ mesenchymal organizer cells and CD45+CD4 ...
Schmutz, Sandrine
core +1 more source
The common gamma chain (γc) contributes to the formation of different cytokine receptors [e.g., IL-2 receptor (IL-2R), IL-7R, and IL-15R], which are important for generation of self-reactive T-cells in autoimmune diseases, like in type 1 diabetes (T1D ...
Julia Seyfarth +8 more
doaj +1 more source
Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify the bone marrow microenvironment and disrupt non-malignant hematopoiesis. However, the molecular mechanisms driving these alterations remain poorly defined.
Xing Feng +8 more
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Mesenchymal stem cells shuttling miR-503 via extracellular vesicles enhance glioma immune escape
Glioma is emerging as an aggressive type of glioma characterized by invasive growth pattern and dismal oncologic outcomes. microRNAs (miRNAs) have been attracting research attention in tumorigenesis.
Xiao-Song Wang +7 more
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The influence of humoral factors of homeostatistic proliferation on t-regulatory cells in vitro
Aim. The aim of this study was the investigation of the influence of humoral factors of homeostatic proliferation IL-7 and IL-15 on T-regulatory cells in healthy donors.Materials and methods.
D. V. Shevyrev +2 more
doaj +1 more source

