Results 221 to 230 of about 1,132,369 (355)
An Allele of the Interleukin-1 Receptor Antagonist as a Genetic Severity Factor in Alopecia Areata
, 1995 Michael J. Cork +7 more
openalex +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Interleukin-1 receptor-associated kinase-1 is a therapeutic target for gastric cancer. [PDF]
Discov OncolShi H, Zhang J, Bao X.
europepmc +1 more source
Advanced Science, EarlyView.This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
wiley +1 more source
Desmoplakin Cardiomyopathy Presenting With Recurrent Myopericarditis Responsive to Interleukin-1 Blockade. [PDF]
JACC Case RepLopez RI +7 more
europepmc +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Tuberculous Meningitis With Paradoxical Reaction in an Immunocompetent Young Male Treated by Interleukin-1 Receptor Antagonist. [PDF]
Case Rep Infect DisKanat A +4 more
europepmc +1 more source
Hypoglycaemic action of interleukin 1 (ILI) and its possible involvement of serotonin (5HT)
, 1995 Yasuo Endo
openalex +1 more source