Results 221 to 230 of about 704,484 (268)

Interleukin-1 and hematopoiesis

Blood Reviews, 1989
Interleukin-1 alpha and interleukin-1 beta are 17.5 kDa peptides which exert a wide variety of biological activities. Both forms of interleukin bind to a common 60-70 kDa receptor expressed by most somatic cells. One major effect of interleukin-1 is to induce the expression of other genes, including genes for other interleukins (IL-6), colony ...
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Neuroendocrinology of Interleukin-1

1990
Inflammatory processes and infectious diseases induce a constellation of host responses referred to as acute phase response (1,2). These responses include changes in immunologic, metabolic, neurologic, and endocrinologic functions. Although many of its components are far from being understood, it is generally believed that the acute phase response ...
F, Berkenbosch, R, de Rijk, A, Del Rey, H, Besedovsky   +3 more
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Interleukin-1 Receptors

1995
Abstract The human type I IL-1 receptor is predicted from the cDNA sequence to be a protein of 569 amino acids (GenBank accession number M27492; mouse, M20658; rat, M95578; chicken, M81846) (Sims et al. 1989). It contains a 20-aminoacid signal peptide, an extracellular region of 317 amino acids, a single 22-amino-acid transmembrane ...
J E, Sims, S K, Dower
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The Interleukin-1 Family

2016
The interleukin-1 (IL-1) family consists of several pro- or anti-inflammatory proteins, with pro-inflammatory IL-1β being its best characterized member. IL-1β is one of the most prominent mediators of inflammation resulting in fever and immune activation via binding to IL-1 receptor 1. Due to its potency, its secretion is tightly regulated.
Amir S, Yazdi, Kamran, Ghoreschi
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Interleukin‐1 in reproductive strategies

Evolution & Development, 2008
SUMMARY Evolutionary studies on different classes of vertebrates could help clarify the role of cytokines in acceptance of the embryo by the maternal tissues. This review focuses on the cytokine interleukin‐1 (IL‐1) and reports on its presence in the female reproductive tract of species with different reproductive strategies, that is, viviparity,
Ricci, Luana, Jantra, SILKE BIRGIT, Ietta, Francesca, Brizzi, R., Bigliardi, Elisa   +4 more
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Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.

Lymphokine research, 1989
IL-1 induces its own gene expression in cultured smooth muscle and endothelial cells and in human PBMC. IL-1-induced IL-1 may be part of a self-amplification or autocrine event in inflammation. In the present study IFN gamma consistently increased LPS-induced IL-1, but reduced the total amount of IL-1-induced IL-1 from PBMC. On a molar basis, IFN gamma
Schindler, R, Ghezzi, P, Dinarello, C A
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The interleukin-1/interleukin-1-receptor interaction

Annales de l'Institut Pasteur / Immunologie, 1987
H R, MacDonald, J W, Lowenthal
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Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease

Circulation Research, 2021

exaly  

Interleukin-1 and interleukin-1 receptor antagonist.

Nutrition (Burbank, Los Angeles County, Calif.), 1996
Cytokines are produced in disease or during immunologic challenge. Some cytokines increase host resistance to disease whereas others trigger inflammatory processes. Interleukin 1 (IL-1) and tumor necrosis factor (TNF) are pro-inflammatory cytokines that affect nearly every cell either alone or in a synergistic fashion.
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Interleukin-1 and Endometriosis

Fertility and Sterility, 1987
Paul G. McDonough, Deborah J. Anderson, Joseph A. Hill   +2 more
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