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Regulation of Interleukin-10 Expression
2016Interleukin (IL)-10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. Loss of IL-10 results in the spontaneous development of inflammatory bowel disease as a consequence of an excessive immune response to the gut microbiota.
Sascha, Rutz, Wenjun, Ouyang
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Gasdermin D pore structure reveals preferential release of mature interleukin-1
Nature, 2021Shiyu Xia +2 more
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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
Nature Reviews Drug Discovery, 2012Charles A Dinarello +2 more
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