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Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2006
Immune loci, characterized by features reflecting their role in defense reactions and consequently related to evolutionary mechanisms, including polymorphisms or association with disease are suitable candidates for comparative analysis. Interleukin-12 and related cytokines are key molecules regulating natural and specific immune responses.
Petr, Kralik +2 more
openaire +2 more sources
Immune loci, characterized by features reflecting their role in defense reactions and consequently related to evolutionary mechanisms, including polymorphisms or association with disease are suitable candidates for comparative analysis. Interleukin-12 and related cytokines are key molecules regulating natural and specific immune responses.
Petr, Kralik +2 more
openaire +2 more sources
Interleukin 12 and autoimmune diabetes
Nature Genetics, 2001Interleukin 12 (IL-12) has been implicated in the pathogenesis of type 1 diabetes in the non-obese diabetic (NOD) mouse. Following this lead, a new locus associated with human type 1 diabetes, IDDM18, has been identified near the gene encoding the p40 subunit of interleukin 12 (IL12B).
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Producer cells of interleukin 12
Parasitology Today, 1993G, Trinchieri +6 more
openaire +2 more sources
Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
Circulation Research, 2021exaly
Biology and therapeutic potential of interleukin-10
Journal of Experimental Medicine, 2020Anne O'Garra +2 more
exaly

