Results 241 to 250 of about 986,782 (400)

Construction of VSVΔ51M oncolytic virus expressing human interleukin-12. [PDF]

Front Mol Biosci, 2023
Abdulal RH, Malki JS, Ghazal E, Alsaieedi AA, Almahboub SA, Khan MY, Alsulaiman RM, Ghaith MM, Abujamel TS, Ganash M, Mahmoud AB, Alkayyal AA, Hashem AM.   +12 more
europepmc   +1 more source

Interleukin 12 shows a better curative effect on lung cancer than paclitaxel and cisplatin doublet chemotherapy [PDF]

, 2016
Ting Yue, Xiaodong Zheng, Yaling Dou, Xiaohu Zheng, Rui Sun, Zhigang Tian, Haiming Wei   +6 more
openalex   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Intraperitoneal administration of mRNA encoding interleukin-12 for immunotherapy in peritoneal carcinomatosis. [PDF]

J Nanobiotechnology
Arrizabalaga L, Di Trani CA, Fernández-Sendin M, Bella Á, Russo-Cabrera JS, Gomar C, Ardaiz N, Belsue V, González-Gomariz J, Zalba S, Gil-Korilis A, Garrido MJ, Melero I, Aranda F, Berraondo P.   +14 more
europepmc   +1 more source

Influence of adalimumab on interleukin 12/23 signalling pathways in human keratinocytes treated with lipopolysaccharide A. [PDF]

Postepy Dermatol Alergol, 2023
Buda P, Michalski P, Warmusz O, Michalska-Bańkowska A, Sirek T, Ossowski P, Bogdał P, Strojny D, Pisany-Syska A, Grabarek BO.   +9 more
europepmc   +1 more source

Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery.

Journal of Infectious Diseases, 2013
S. Kalams, Scott D. Parker, M. Elizaga, B. Metch, S. Edupuganti, J. Hural, Stephen C. De Rosa, D. Carter, K. Rybczyk, I. Frank, J. Fuchs, B. Koblin, Denny H Kim, P. Joseph, M. Keefer, L. Baden, J. Eldridge, J. Boyer, Adam I Sherwat, M. Cardinali, M. Allen, M. Pensiero, C. Butler, Amir S. Khan, Jian Yan, N. Sardesai, J. Kublin, D. Weiner   +27 more
semanticscholar   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

RETRACTION: "Effect of Interleukin‑12 Gene Expression on Insulin Resistance in Patients With Acne Vulgaris". [PDF]

Skin Res Technol
europepmc   +1 more source

Combination of mechanical debridement and interleukin 12 or interleukin 23 therapy for refractory facial pyoderma gangrenosum with NOD2 mutation. [PDF]

JAAD Case Rep
Vague M, Shea M, Thacker S, Onoday H, Ortega Loayza AG.   +4 more
europepmc   +1 more source

The combination of plasmid interleukin‐12 with a single DNA vaccine is more effective than Mycobacterium bovis (bacille Calmette–Guèrin) in protecting against systemic Mycobacterim avium infection

, 2003
E. Martin, Arun T. Kamath, Helen Briscoe, Warwick J. Britton   +3 more
openalex   +1 more source