Results 221 to 230 of about 986,782 (400)

Diagnostic value of macrophage inflammatory protein-1α, plasma thrombomodulin, and interleukin 12 in stroke-associated infections. [PDF]

Am J Transl Res
Song S, Xie R.
europepmc   +1 more source

Association and Interaction Effects of Interleukin-12 Related Genes and Physical Activity on Cognitive Aging in Old Adults in the Taiwanese Population [PDF]

, 2019
Eugene Lin, Po‐Hsiu Kuo, Yu-Li Liu, Albert C. Yang, Shih‐Jen Tsai   +4 more
openalex   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Interleukin-12 as a Predictor for Unresponsiveness to the Hepatitis B Vaccine: A Novel Cut-Off Point in Children. [PDF]

Children (Basel)
Ermaya YS, Sribudiani Y, Ghrahani R, Hock QS, Prasetyo D.   +4 more
europepmc   +1 more source

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes.

Blood, 1994
G. Trinchieri
semanticscholar   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

CCAAT/enhancer-binding protein delta regulates miRs-4257 and 3156 to attenuate the interleukin 12 through small extracellular vesicle transmission in glioblastoma. [PDF]

Cancer Cell Int
Chu YY, Ko CY, Wang SM, Wang WJ, Wang CY, Chen FW, Liang HY, Wang JM.   +7 more
europepmc   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Evolutionary insights into Interleukin-12 family targets across 405 species. [PDF]

Front Immunol
Wang W, Li D, Luo K, Chen B, Li X, Hao T, Guo D, Dong Y, Ning Y.   +8 more
europepmc   +1 more source

Image 1_Evolutionary insights into Interleukin-12 family targets across 405 species.tif

Weibin Wang (1968658), Dawei Li (5704), Kaiyong Luo (21448442), Baozheng Chen (10944447), Xuzhen Li (21448445), Tingting Hao (107457), Dazhong Guo (21448448), Yang Dong (234336), Ya Ning (19855101)   +8 more
openalex   +1 more source