Antitumor properties of traditional lactic acid bacteria: Short-chain fatty acid production and interleukin 12 induction. [PDF]
Mobasherpour P +2 more
europepmc +1 more source
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source
Oncolytic varicella-zoster virus engineered with ORF8 deletion and armed with drug-controllable interleukin-12. [PDF]
Jiang H +5 more
europepmc +1 more source
Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat.
Terence Smith +4 more
openalex
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan +24 more
wiley +1 more source
Serum Levels of IL-35, One of the Newest Members of Interleukin-12 Family of Cytokines, in Patients With Vitiligo. [PDF]
Hayran Y +5 more
europepmc +1 more source
Differential detection of chicken heterodimeric cytokines, interleukin 12 and 23 using their subunit-specific mouse monoclonal antibodies. [PDF]
Lee Y, Kim WH, Nam H, Lillehoj HS.
europepmc +1 more source
Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder. [PDF]
Sarmin N +4 more
europepmc +1 more source
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Novel strategies exploiting interleukin-12 in cancer immunotherapy.
Pharmacology and Therapeutics, 2022Interleukin-12 is considered a potent agent to enhance antitumor immune responses. It belongs to a family of heterodimeric cytokines with key roles in the up-regulation and down-regulation of cellular immunity.
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