Results 241 to 250 of about 63,752,558 (296)

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

The role of interleukin-17 in inflammation-related cancers. [PDF]

Front Immunol
Zhang X, Li B, Lan T, Chiari C, Ye X, Wang K, Chen J.   +6 more
europepmc   +1 more source

Dual signaling cascade regulating gut-lung axis in Interleukin-6/Interleukin-17 for NSCLC immuno pathogenesis. [PDF]

Front Immunol
Khilwani R, Singh S.
europepmc   +1 more source

Theogallin Protects Myocardial Ischemia-Reperfusion Injury by Inhibiting the Interleukin-17 Signaling Pathway. [PDF]

J Agric Food Chem
Zhu F, Cheng H, Luo Z, Cao A, Yu T, Ge H, Hu S, Xie Z, Li D.   +8 more
europepmc   +1 more source

Interleukin-17 Inhibitors in the Treatment of Hidradenitis Suppurativa. [PDF]

BioDrugs
Pinto Salgueiro G, Yilmaz O, Nogueira M, Torres T.   +3 more
europepmc   +1 more source

Eutopic and Ectopic Endometrial Interleukin-17 and Interleukin-17 Receptor Expression at the Endometrial-Myometrial Interface in Women with Adenomyosis: Possible Pathophysiology Implications. [PDF]

Int J Mol Sci
Hsu LT, Lu PC, Wang YW, Wu HM, Chen IJ, Huang HY.   +5 more
europepmc   +1 more source

Expert Opinion Report on the Challenges in the Management of Psoriatic Arthritis in United Arab Emirates: A Focus on Interleukin-17 Inhibitors. [PDF]

Open Access Rheumatol
Abogamal A, Badsha H, Hannawi S, Harifi G, Khan B, Ansari AA, Alnaqbi KA, Zayat AS, Ibrahim S, Taher M, Namas R.   +10 more
europepmc   +1 more source

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Interleukin-17

International Reviews of Immunology, 1998
The particular interest of IL-17, a homodimeric cytokine of about 32 kDa, is the strict requirement for an activation signal to induce its expression from a rather restricted set of cells, human memory T cells or mouse alpha beta TCR+CD4-CD8- thymocytes.
F, Fossiez, J, Banchereau, R, Murray, C, Van Kooten, P, Garrone, S, Lebecque   +5 more
openaire   +2 more sources

Measurement of Interleukin‐17

Current Protocols in Immunology, 2007
AbstractUpon antigenic stimulation, naive CD4+ T cells undergo proliferation and differentiate into cytokine‐producing T helper (TH) effector cells. TH1 cells secrete effector cytokine IFN‐γ and regulate cell‐mediated immunity, whereas TH2 cells produce IL‐4, IL‐5, and IL‐13 cytokines, and mediate immunity against extracellular pathogens and allergic ...
Bhanu P, Pappu, Chen, Dong
openaire   +2 more sources

Interleukin-8 and Interleukin-17 for Cancer

Cancer Investigation, 2014
Pro-inflammatory cytokines have been associated with chronic inflammation and inflammatory diseases. Increased levels of interleukins (ILs) have been associated with inflammatory disease exacerbation. ILs levels have been observed to be associated with advance stage cancer for several types of cancer and a poor prognostic maker for malignant disease ...
Paul, Zarogoulidis, Fotini, Katsikogianni, Theodora, Tsiouda, Antonios, Sakkas, Nikolaos, Katsikogiannis, Konstantinos, Zarogoulidis   +5 more
openaire   +2 more sources