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Frontiers in Medicine, 2019 Interleukin (IL)-17A has a direct contribution in early induction and late chronic stages of various inflammatory diseases. In vitro and in vivo experiments have first characterized its local effects on different cell types and then its systemic effects.
Marie Robert, Pierre Miossec
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Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]
, 2017 BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki +8 more
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Interleukin‐17 and ischaemic stroke [PDF]
Immunology, 2020 SummaryInterleukin‐17 (IL‐17) is a cytokine family that includes 6 members, IL‐17A through IL‐17F, most of them are reported to have pro‐inflammatory role. Through binding to their receptors (IL‐17Rs), IL‐17 activates the intracellular signalling pathways to play an important role in autoimmune diseases, including rheumatoid arthritis (RA) and multiple
Qiaohui Zhang +6 more
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T helper type 17 in psoriasis: From basic immunology to clinical practice
Dermatologica Sinica, 2012 Psoriasis is a chronic inflammatory disease mediated by a complex interplay between immune system and keratinocytes. Initially considered as a keratinocyte proliferation/differentiation disorder, an immune dysregulation was confirmed after the successful
Hsien-Yi Chiu +2 more
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Granulocyte-activating mediators (GRAM) [PDF]
, 1988 In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A. +3 more
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Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
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The Saudi Journal of Gastroenterology, 2018 Background/Aim: We studied the expression of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter (LES) in healthy individuals and in patients diagnosed with achalasia (AC) to gain a better understanding of the ...
Zeyu Wang +4 more
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International Journal of Preventive Medicine, 2019 Background: Periimplant diseases are inflammatory diseases. Thus, the level of preinflammatory cytokines which has important role in the inflammation processes can consider as biomchemical markers for early diagnosis and prevention of periimplant ...
Shirin Zahra Farhad +2 more
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Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs : involvement of MAPK and NF-κB pathways [PDF]
, 2014 The terpenoid 17-O-acetylacuminolide (AA) was shown to inhibit the production of several inflammatory mediators. However, the mechanisms by which this compound elicited its anti-inflammatory activity remain to be elucidated.
Achoui, Mouna +5 more
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BMC Rheumatology, 2020 Background Osteoarthritis (OA) is a progressive, chronic disease characterized by articular cartilage destruction. The pro-inflammatory cytokine IL-17 levels have been reported elevated in serum and synovial fluid of OA patients and correlated with ...
Dovile Sinkeviciute +4 more
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