Results 31 to 40 of about 4,008,604 (402)

Current concepts in the pathogenesis of spondyloarthritis

open access: yesIndian Journal of Rheumatology, 2020
Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj   +1 more source

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]

open access: yes, 2018
Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M.   +5 more
core   +1 more source

Ekstrak Etanol Propolis Menurunkan Kadar IL-17 Serum pada Mencit Balb/C Model Asma Kronik

open access: yesMajalah Kedokteran Bandung, 2013
Interleukin-17 (IL-17) induces the neutrophil recruitment into the respiratory tract while playing a role in the pathogenesis of asthma and determining the severity of disease.
Sri Hartati Hadinoto   +3 more
doaj   +1 more source

Interleukin-17 in Chronic Inflammatory Neurological Diseases

open access: yesFrontiers in Immunology, 2020
A critical role for IL-17, a cytokine produced by T helper 17 (Th17) cells, has been indicated in the pathogenesis of chronic inflammatory and autoimmune diseases.
J. Milovanović   +7 more
semanticscholar   +1 more source

T helper type 17 in psoriasis: From basic immunology to clinical practice

open access: yesDermatologica Sinica, 2012
Psoriasis is a chronic inflammatory disease mediated by a complex interplay between immune system and keratinocytes. Initially considered as a keratinocyte proliferation/differentiation disorder, an immune dysregulation was confirmed after the successful
Hsien-Yi Chiu   +2 more
doaj   +1 more source

Recovery of interleukin-17 production from interleukin-15-stimulated CD4+ mononuclear cells in HIV-1-infected patients with sustained viral suppression [PDF]

open access: yes, 2014
Interleukin-17 (IL-17) is a pro-inflammatory cytokine that is mainly produced by CD4 + T cells. The role of Th17 during the human immunodeficiency virus (HIV)-1 infection is still unclear, but HIV-1 infection can cause a preferential depletion of Th17 ...
ASCOLI BARTOLI, Tommaso   +9 more
core   +1 more source

IL-17 in Rheumatoid Arthritis and Precision Medicine: From Synovitis Expression to Circulating Bioactive Levels

open access: yesFrontiers in Medicine, 2019
Interleukin (IL)-17A has a direct contribution in early induction and late chronic stages of various inflammatory diseases. In vitro and in vivo experiments have first characterized its local effects on different cell types and then its systemic effects.
Marie Robert, Pierre Miossec
doaj   +1 more source

Biology of Interleukin-17 and Its Pathophysiological Significance in Sepsis

open access: yesFrontiers in Immunology, 2020
The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer.
Yun Ge, Man Huang, Yong-ming Yao
semanticscholar   +1 more source

Airway neutrophils and interleukin-17 [PDF]

open access: yesEuropean Respiratory Journal, 2000
It is well known that exacerbations of obstructive airways disease such as asthma and chronic obstructive pulmonary disease are associated with an increased number of neutrophils in the airways. However, the mechanisms behind this phenomenon are poorly understood.
Martti Laan   +2 more
openaire   +3 more sources

Expression and significance of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter of patients with achalasia

open access: yesThe Saudi Journal of Gastroenterology, 2018
Background/Aim: We studied the expression of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter (LES) in healthy individuals and in patients diagnosed with achalasia (AC) to gain a better understanding of the ...
Zeyu Wang   +4 more
doaj   +1 more source

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