Results 201 to 210 of about 199,768 (345)
Intraplantar β-Caryophyllene Alleviates Pain and Inflammation in STZ-Induced Diabetic Peripheral Neuropathy via CB<sub>2</sub> Receptor Activation. [PDF]
Bagher AM.
europepmc +1 more source
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan+12 more
wiley +1 more source
The monomeric but not homotrimeric spike protein of SARS-CoV-2 activates TLR4 signaling. [PDF]
Lübow C, Weindl G.
europepmc +1 more source
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source
Updates in the Management of Hereditary Periodic Fever Syndromes in Children. [PDF]
Tripathy SK+4 more
europepmc +1 more source
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu+18 more
wiley +1 more source
The Chemokine (C-C Motif) Receptor 1 Antagonist BX471 Improves Fluid Resuscitation in Rat Models of Hemorrhagic Shock. [PDF]
Cook EA+3 more
europepmc +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
The Golden Card of Interleukin-1 Blockers in Systemic Inflammasomopathies of Childhood. [PDF]
Rigante D.
europepmc +1 more source