Results 131 to 140 of about 60,800,054 (257)
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22. [PDF]
World J Gastrointest Surg, 2023 Zhou H +6 more
europepmc +1 more source
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Interleukin-17 und Interleukin-22: Schlüsselzytokine in der Gewebeentzündung
, 2013 IL-17 and IL-22 are signature cytokines of T helper (Th) 17 and Th22 cells linking adaptive and innate immune responses via modulation of epithelial cell functions. The present thesis demonstrates that pro- and anti- inflammatory functions of Interleukin
Pennino, Davide
core
Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]
, 2010 PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core
Advanced Science, EarlyView.A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia +10 more
wiley +1 more source
Interleukin-22 binding protein in multiple sclerosis and experimental inflammation models
, 2017 Multiple sclerosis (MS) is the leading cause of non-traumatic neurological disability in young adults. Although the cause of the disease is unknown, several genetic and environmental risk factors have been identified.
Hannes Lindahl (18671536)
core +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
, 2019 Interleukin-22 level and vascular remodeling in patients with hypertension in associated with abdominal ...
Kovalyova, Olga, Kysylenko, Kateryna
core