Results 41 to 50 of about 417,438 (262)

The anti-inflammatory and protective role of interleukin-38 in inflammatory bowel disease. [PDF]

J Clin Biochem Nutr, 2022
Interleukin (IL)-38 exerts an anti-inflammatory function by binding to several cytokine receptors, including the IL-36 receptor. In this study, we evaluated IL-38 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD) and investigated its functions.
Ohno M, Imai T, Chatani M, Nishida A, Inatomi O, Kawahara M, Hoshino T, Andoh A.   +7 more
europepmc   +4 more sources

Immunobiological Properties and Clinical Applications of Interleukin-38 for Immune-Mediated Disorders: A Systematic Review Study. [PDF]

Int J Mol Sci, 2021
Exponential growth in the usage of “cytokines” (as seroimmunobiomarkers) has facilitated more accurate prognosis, early diagnosis, novel, and efficient immunotherapeutics.
Esmaeilzadeh A, Bahmaie N, Nouri E, Hajkazemi MJ, Zareh Rafie M.   +4 more
europepmc   +2 more sources

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN, Willeit, P, Trip, MD, Willeit, J, Nelson, Christopher P, Samani, NJ, Danesh, J, Psaty, Bruce M., Assimes, Themistocles L., Stringham, Heather M, Kastelein, JJP, Adamovic, Svetlana, Franks, Paul W., Trip, Mieke D, Harris, Tamara B, Meade, TW, Thomas, Graham; id_orcid, Tivesten, A, de Bakker, PIW, Tybjærg-Hansen, Anne, Boehnke, M, de Bakker, Paul IW, Wilson, Anthony G, Trip, Mieke D., Witteman, Jacqueline C. M., Freitag, DF, Sarwar, Nadeem, Gao, P, Gallacher, John Edward, Ljunggren, Osten, Qi, Lu, Hall, Alistair S., Samani, Nilesh J., Karlsson, Magnus, Hofman, Bert, Goodall, AH, Watkins, H, Arbor, Ann, Davey Smith, George, Chambers, John C, Shaffer, Jonathan A, Butterworth, Adam S., Tracy, Russell P, O'Donnell, CJ, Gorman, Donal N., Psaty, Bruce M, Panagiotakos, DB, Wilde, Arthur AM, Best, LG, Di Angelantonio, Emanuele, Sundstrom, J, Butterworth, AS, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.), Cambien, Francois, Gregson, J, Gorman, Donal N, Best, Lyle G., Manson, JE, Rimm, Eric B, Wennberg, P, de Bakker, Paul I. W., Melzer, D, Qi, L, Gillum, Richard F, Kleber, ME, Gallacher, John, Kastelein, John JP, Chasman, DI, Cambien, F, Ridker, Paul M, Salomaa, Veikko, Hall, AS, Benjamin, Emelia J., Chasman, Daniel I, Salonen, JT, Kaptoge, S, Salonen, Jukka T., O'Donnell, Christopher J., Ingelsson, Erik, Benjamin, Emelia J, Freitag, Daniel F, Rader, Daniel J., Tracy, Russell P., Salonen, Jukka T, Saleheen, D, ?, ?, Salomaa, V, Clarke, Robert, Kleber, Marcus E., Chambers, JC, Witteman, Jacqueline C M, Braund, Peter S., Manson, JoAnn E., Boehnke, Michael, Ouwehand, Willem H, Rendon, A, Wilson, Anthony G., Harari, Olivier, Hopewell, Jemma C., Wilson, AG, Tracy, RP, Karlsson, M, Cantin, B, Reilly, Muredach P., Ohlsson, C, Melzer, David, IL6R Genetics Consortium Emerging Risk Factors Collaboration, Meade, Tom W, Jansson, J-O, Benjamin, EJ, Stringham, Heather M., Freitag, Daniel F., Cantin, Bernard, Gregson, John, Chasman, Daniel I., Butterworth, Adam S, Reich, David, Braund, PS, Schunkert, H, Di Angelantonio, E, Ouwehand, WH, Harris, Tamara B., Thomas, G. Neil, Allin, Kristine H., Nelson, CP, Allin, Kristine Højgaard, Best, Lyle G, de Faire, Ulf, Davey-Smith, George, Kooner, Jaspal S, Gudnason, Vilmundur, Emerging, IGC, Rimm, Eric B., Shaffer, Jonathan A., Sundstrom, Johan, Jansson, JO, Erdmann, Jeanette, Steri, M, Kauhanen, J, Holm, H, Samani, Nilesh J, Nordestgaard, BG, Mellstrom, Dan, Rader, Daniel J, Kaptoge, Stephen, Goodall, Alison H., Meade, Tom W., Clarke, R, Shaffer, JA, Ben-Shlomo, Yoav, Wilson, James F, Witteman, JCM, Ridker, PM, Davey-Smith, G, Tivesten, Asa, Koenig, W, Franks, Paul W.,, O'Donnell, Christopher J, Allin, Kristine H, van der Schoot, CE, Reilly, MP, Asselbergs, FW, Nelson, Christopher P., Hung, J, Danesh, John, Witteman, Jacqueline CM, Gudnason, V, Adamovic, S, Holm, Hilma, Kleber, Marcus E, Cushman, M, Ljunggren, Östen,, Erdmann, J, Koenig, Wolfgang, Rimm, EB, Hung, Joseph, Asselbergs, Folkert W., van der Schoot, C. Ellen, Wassertheil-Smoller, S, Kooner, Jaspal S., Panagiotakos, Demosthenes B, Franks, Paul, Willeit, Peter, Nordestgaard, Børge G, Kooner, JS, Chambers, John C., Tybjaerg-Hansen, Anne, Nordestgaard, Borge G., Tybjaerg-Hansen, A, Kauhanen, Jussi, Wilde, Arthur A. M., Gillum, RF, Watkins, Hugh, Mellstrom, D, Thomas, G Neil, Sarwar, N, de Faire, U, Wilde, AAM, Psaty, BM, Ben-Shlomo, Y, Panagiotakos, Demosthenes B., Ljunggren, O, Harris, TB, Sundström, Johan,, Reilly, Muredach P, Wilde, Arthur A M, Asselbergs, Folkert W, Woodward, Mark, Stringham, HM, Harari, O, Saleheen, Danish, Schunkert, Heribert, Hall, Alistair S, Cushman, Mary, Gorman, DN, Gillum, Richard F., Hofman, A, Hopewell, Jemma C, Wilson, JF, IL6R Genetics Consortium, Rader, DJ, Wilson, James F., Kastelein, John J. P., Woodward, M, Hopewell, JC, Hofman, Albert, Rendon, Augusto, Wennberg, Patrik, Jansson, John-Olov, Wilhelmsen, L, Reich, D, Manson, JoAnn E, Onat, A, Amouyel, Philippe, Hamsten, A, Ingelsson, E, Franks, Paul W, Willeit, Johann, Onat, Altan, Wilhelmsen, Lars, Assimes, Themistocles L, Gallacher, J, Wassertheil-Smoller, Sylvia, van der Schoot, C Ellen, Assimes, TL, Goodall, Alison H, Franks, PW, Amouyel, P, Steri, Maristella, Ohlsson, Claes, Braund, Peter S, Allin, KH, Hamsten, Anders, Ridker, Paul M., Ouwehand, Willem H., Gao, Pei   +255 more
core   +2 more sources

Interleukin-38 in colorectal cancer: a potential role in precision medicine. [PDF]

Cancer Immunol Immunother, 2020
Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising sensitive/specific marker(s).
Chen F, Zhang F, Tan Z, Hambly BD, Bao S, Tao K.   +5 more
europepmc   +3 more sources

Interleukin 38 Protects Against Lethal Sepsis [PDF]

The Journal of Infectious Diseases, 2018
Interleukin 38 (IL-38) is the most recently characterized cytokine of the interleukin 1 family. However, its role in sepsis remains unknown.Circulating IL-38 levels were measured in 2 cohorts of adult and pediatric patients with sepsis. Using 2 murine models of lipopolysaccharide (LPS)-induced endotoxemia and cecal ligation and puncture (CLP)-induced ...
Fang, Xu, Shihui, Lin, Xingxing, Yan, Chuanjiang, Wang, Hongmei, Tu, Yibing, Yin, Ju, Cao   +6 more
openaire   +2 more sources

Evaluating the Role of Interleukin-36 and Interleukin-38 in Acne Vulgaris Patients [PDF]

Benha Journal of Applied Sciences, 2020
Interleukin (IL)- 36 and (IL)- 38 cytokines are individuals from the IL-1 family, which incorporate favorable to infammatory factors and over late years, much has been educated on their significant capacities in the guideline of safe reaction and, particularly, on their function in numerous infammatory skin sicknesses.
F.M. El-Esawy, D.M. Elhabak, S.A. Mohamed, S.H. Mostafa   +3 more
openaire   +1 more source

Anti-inflammatory Mechanisms of IL-38 in Chinese Patients with Allergic Rhinitis [PDF]

Iranian Journal of Immunology, 2023
Background: T-helper 17 (Th17) cell response is engaged in the onset of allergic rhinitis (AR). Moreover, interleukin (IL)-38 is thought to be involved in inhibiting cytokine secretion in the Th17 pathway.Objective: To evaluate the regulatory function of
Xiaoqiang Wang, Yang Shen, Xia Ke, Suling Hong   +3 more
doaj   +1 more source

Elevated Interleukin-38 Level Associates with Clinical Response to Atorvastatin in Patients with Hyperlipidemia

Cellular Physiology and Biochemistry, 2018
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang, Yanqiu Song, Bo Dong, Yang Li, Lu Kou, Jingyu Yang, Qin Qin   +6 more
doaj   +1 more source

Evaluation of serum interleukin-36, interleukin-37 and interleukin-38 levels in rosacea patients [PDF]

, 2021
Tıp Fakültesi, Deri ve Zührevi Hast. Ana Bilim DalıGiriş ve Amaç: Rozasea, patogenezi halihazırda net olarak aydınlatılamamış olan, ön planda yüz cildinde dışbükey bölgelerde eritem, telenjiektazi, papül, püstül ve fimatöz lezyonlarla karakterize olan ve
Ekinci, Alper
core  

DataSheet_1_Circulating interleukin-38 concentrations in healthy adults.docx

, 2022
Interleukin (IL)-38 is the latest discovered member of the interleukin-1 family, which has anti-inflammatory properties similar to IL-36Ra. Several studies compared circulating IL-38 concentrations in healthy and diseased populations to characterize its ...
Charles A. Dinarello (7623869), Dennis M. de Graaf (12641875), Lisa U. Teufel (11473772), Mihai G. Netea (7241447), Leo A. B. Joosten (7547705), Rob J. W. Arts (4443052)   +5 more
core   +1 more source