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Interleukin-38 in Health and Disease [PDF]

Cytokine, 2022
Contains fulltext : 252005.pdf (Publisher’s version ) (Open Access)
Graaf, D.M. de, Teufel, L.U., Joosten, L.A.B., Dinarello, C.A.   +3 more
openaire   +3 more sources

Interleukin-38 as a potential diagnostic biomarker for heart failure. [PDF]

Biomark Med
Interleukin-38 (IL-38) attenuates inflammation, myocardial injury, and ventricular remodeling after myocardial infarction, which potentially reduces the incidence of heart failure (HF). This study aimed to evaluate the diagnostic value of IL-38 for HF.IL-38 was detected via enzyme-linked immunosorbent assay in the serum samples of 238 hF patients and ...
Liu H, Zhang M, Gong W, Tian F, Zhang L, Zhao J, Xiang B, Hui J.   +7 more
europepmc   +3 more sources

Interleukin-38 promotes skin tumorigenesis in an IL-1Rrp2-dependent manner. [PDF]

EMBO Rep, 2022
Interleukin-38 (IL-38) is strongly associated with chronic inflammatory diseases; however, its role in tumorigenesis is poorly understood. We demonstrated that expression of IL-38, which exhibits high expression in the skin, is downregulated in human cutaneous squamous cell carcinoma and 7,12-dimethylbenzanthracene/12-O-tetradecanoyl phorbol-13-acetate-
Zhou H, Zhao Q, Yue C, Yu J, Zheng H, Hu J, Hu Z, Zhang H, Teng X, Liu X, Wei X, Zhou Y, Zeng F, Hao Y, Hu Y, Wang X, Zhang C, Gu L, Wu W, Zhou Y, Cui K, Huang N, Li W, Wang Z, Li J.   +24 more
europepmc   +3 more sources

Interleukin-38 promoter variants and risk of COVID-19 among Iraqis. [PDF]

Immunobiology, 2022
Coronavirus disease-19 (COVID-19) has recently emerged as a respiratory infection with a significant impact on health and society. The pathogenesis is primarily attributed to a dysregulation of cytokines, especially those with pro-inflammatory and anti-inflammatory effects. Interleukin-38 (IL-38) is a recently identified anti-inflammatory cytokine with
Al-Karaawi IA, Al-Bassam WW, Ismaeel HM, Ad'hiah AH.   +3 more
europepmc   +3 more sources

Retraction 'Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression'. [PDF]

Open Biol, 2020
Wang F, Zhang W, Wu T, Chu H.
europepmc   +2 more sources

Imbalance of expression levels of IL-36γ and IL-38 is possibly associated with the severity of inflammation in psoriasis vulgaris

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To investigate the roles of cytokines, IL-36γ and IL-38, in the inflammatory response in psoriasis vulgaris. Methods Both serum and peripheral blood mononuclear cells (PBMC) were collected from 29 patients with psoriasis vulgaris (PV) and 19 ...
Jiao ZHANG, Liujun LU, Hang SU, Liyan YUAN, Yongfeng CHEN   +4 more
doaj   +1 more source

Interleukin-38 alleviates cardiac remodelling after myocardial infarction. [PDF]

J Cell Mol Med, 2020
AbstractExcessive immune‐mediated inflammatory reaction plays a deleterious role in ventricular remodelling after myocardial infarction (MI). Interleukin (IL)‐38 is a newly characterized cytokine of the IL‐1 family and has been reported to exert a protective effect in some autoimmune diseases.
Wei Y, Lan Y, Zhong Y, Yu K, Xu W, Zhu R, Sun H, Ding Y, Wang Y, Zeng Q.   +9 more
europepmc   +4 more sources

Imbalance between serum interleukin-36 and interleukin-38 is associated with metabolic syndrome in psoriasis vulgaris

Journal of the Egyptian Women’s Dermatologic Society, 2023
Background In psoriasis, interleukin (IL)-36 is considered a pathogenic driver, whereas IL-38 was downregulated. Little is known about their role in metabolic syndrome (Ms) in psoriasis.
Marwa A Amer, Doaa M Mahgoub, Dina Kadry, Ghada R.A Ahmed, Laila A Rashed, Basma A Gaballah, Marwa M Kamel   +6 more
doaj   +1 more source

Interleukin‐38: A crucial player in periodontitis

Oral Diseases, 2023
Abstract Background The objective of this study was to compare the levels of gingival crevicular fluid (GCF), salivary, and serum matrix metalloproteinase‐9, interleukin (IL)‐17, IL‐36γ, and IL‐38 in individuals with healthy periodontium, gingivitis, and periodontitis and to evaluate their ...
Hilal Korkmaz, Mükerrem Hatipoğlu, Nezahat Arzu Kayar   +2 more
openaire   +2 more sources

Evaluation of interleukin-38 levels in serum of patients with coronavirus disease 2019. [PDF]

J Med Virol, 2022
Abstract Interleukin‐38 (IL‐38) has recently been considered as a cytokine with anti‐inflammatory properties in viral respiratory infections, particularly coronavirus disease 19 (COVID‐19), but the evidence has not been well elucidated.
Al-Bassam WW, Al-Karaawi IA, Sharquie IK, Ad'hiah AH.   +3 more
europepmc   +3 more sources