Results 31 to 40 of about 1,051,125 (350)

Signaling via interleukin-4, receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice [PDF]

, 2001
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson S., Anderson S., Anderson S., Artis D., Bancroft A. J., Bancroft A. J., Barner M., Belkaid Y., Brewer J. M., Brombacher F., Coulson P. S., D'Andrea A., de Andres B., Dean D. A., Delgado V., Donaldson D. D., Faquim-Mauro E. L., Galbiati F., Grunig G., Guler M. L., Hilton D. J., Hoffmann K. F., Hsieh C. S., James S. L., Jankovic D., Jankovic D., Jankovic D., King C. L., King C. L., Kopf M., Magram J., Mangold B. L., Matthews D. J., Mattner F., McKenzie G. J., Metwali A., Mohrs M., Mohrs M., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Muchamuel T., Nelms K., Noben-Trauth N., Noben-Trauth N., Noben-Trauth N., O'Garra A., Pearce E. J., Reiner S. L., Scott P., Seder R. A., Sher A., Shibuya K., Smythies L. E., Smythies L. E., Street M., Szabo S. J., Urban J. F., Wilson R. A., Wynn T. A., Wynn T. A., Zurawski G.   +64 more
core   +2 more sources

Association of interleukin 10 rs1800896 polymorphism with susceptibility to breast cancer: a meta-analysis. [PDF]

, 2020
Objective: To evaluate the correlation between interleukin 10 (IL-10) -1082A/G polymorphism (rs1800896) and breast cancers by performing a meta-analysis.
Liu, Ji-Bin, Liu, Xi, Qian, LinXue, Zhu, ZiYin   +3 more
core   +2 more sources

Indicators of cytokines in children with hepatobiliary pathology combined with parasitosis

Gastroenterologìa, 2018
Background. Hepatobiliary pathology (HBP) in children tend to continual growth, and the pathology itself is characterized by a group of features that are absent in adults.
T.V. Sorokman, N.A. Popelyuk, L.V. Shvygar   +2 more
doaj   +3 more sources

Interleukin-2 therapy in patients with HIV infection [PDF]

, 2009
BACKGROUND Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increases is not known.
Aagaard, B., Abrams, D., Angus, B., Aragon, E., Arnaiz, J., Babiker, A., Borup, L., Clotet, B., Collins, G., Cooper, D. A., Cordwell, B., Darbyshire, J., Dodds, W., Dragsted, U., Emery, S., Fau, A., Fleck, S., Fox, L., Gey, D., Gordin, F., Grarup, J., Grijsen, M., Hengge, U., Herrero, P., Jansson, P., Jensen, B., Jensen, K., Juncher, H., Lane, H. C., Lange, J., Langebeek, N., Lopez, P., Losso, M. H., Lundgren, J., Lundgren, J. D., Lévy, Y., Matthews, C., Mitsuyasu, R., Mollerup, D., Neaton, J. D., Pearson, M., Phillips, A., Reilev, S., Reiss, P., Routy, J. P., Tambussi, G., Tillmann, K., van der Horst, C., Varea, S., Wentworth, D.   +49 more
core   +6 more sources

The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma

Frontiers in Pharmacology, 2019
Approximately 5–10% of asthmatic patients worldwide suffer from severe asthma. Experimental and clinical studies have demonstrated that IL-13 is an important cytokine in chronic airways inflammation.
Giancarlo Marone, Giancarlo Marone, Francescopaolo Granata, Francescopaolo Granata, Valentina Pucino, Antonio Pecoraro, Enrico Heffler, Enrico Heffler, Stefania Loffredo, Stefania Loffredo, Stefania Loffredo, Guy W. Scadding, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +14 more
doaj   +1 more source

Interleukin 4 Affects Epilepsy by Regulating Glial Cells: Potential and Possible Mechanism

Frontiers in Molecular Neuroscience, 2020
Epilepsy is a chronic brain dysfunction induced by an abnormal neuronal discharge that is caused by complicated psychopathologies. Recently, accumulating studies have revealed a close relationship between inflammation and epilepsy.
Lu Chen, Lin Zhu, Di Lu, Zhe Wu, Yanbing Han, Puying Xu, Lvhua Chang, Qian Wu   +7 more
doaj   +1 more source

Interleukin-4/interleukin-4 receptor gene polymorphisms in hand osteoarthritis [PDF]

Osteoarthritis and Cartilage, 2010
IL-13/IL-4/IL-4R system has strong chondroprotective activity. We investigated polymorphisms in these genes as potential hand osteoarthritis (OA) susceptibility loci by performing a case-control association study.Eighteen common single nucleotide polymorphisms (SNPs) (nine in IL-4R, five in IL-4 and four in IL-13) were genotyped in 403 patients (380 ...
Vargiolu M., Silvestri T., BONORA, ELENA, Dolzani P., Pulsatelli L., ADDIMANDA, OLGA, Mancarella L., Punzi L., Fioravanti A., FACCHINI, ANDREA, ROMEO, GIOVANNI, MELICONI, RICCARDO   +11 more
openaire   +4 more sources

Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]

, 2018
open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of

core   +1 more source

Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice

Memorias do Instituto Oswaldo Cruz, 2010
Protein-energy malnutrition and micronutrient deficiencies may down-regulate immune response and increase morbidity and mortality due to infection. In this study, a murine model was used to study the effects of protein, iron and zinc deficiencies on the ...
Tiago Donatelli Serafim, Guilherme Malafaia, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa, Simone Aparecida Rezende   +4 more
doaj   +1 more source

Functional Haplotypes in Interleukin 4 Gene Associated with Periodontitis. [PDF]

PLoS ONE, 2017
Chronic periodontitis (CP) is an infectious inflammatory disease that affects tooth-supporting structures and in which dental plaque bacteria, immune mechanisms and genetic predisposition play important roles.
Giovana Anovazzi, Marcell Costa de Medeiros, Suzane Cristina Pigossi, Livia Sertori Finoti, Marcia Pinto Alves Mayer, Carlos Rossa, Raquel Mantuaneli Scarel-Caminaga   +6 more
doaj   +1 more source