Results 11 to 20 of about 9,696,955 (392)
Interleukin-6 Family Cytokines [PDF]
Cold Spring Harbor Perspectives in Biology, 2017 The interleukin (IL)-6 family cytokines is a group of cytokines consisting of IL-6, IL-11, ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin 1 (CT-1), cardiotrophin-like cytokine (CLC), and IL-27. They are grouped into one family because the receptor complex of each cytokine contains two (IL-6 and ...
S. Rose-John
openaire +3 more sources
The Role of Interleukin 6 During Viral Infections
Frontiers in Microbiology, 2019 Lauro Velazquez-Salinas +4 more
doaj +2 more sources
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
medRxiv, 2021 Background: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: We evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform ...
A. Gordon +61 more
semanticscholar +1 more source
Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
Circulation Research, 2021 IL (interleukin)-6 is a pivotal cytokine of innate immunity, which enacts a broad set of physiological functions traditionally associated with host defense, immune cell regulation, proliferation, and differentiation.
P. Ridker, Manas Rane
semanticscholar +1 more source
Interleukin 6: at the interface of human health and disease
Frontiers in Immunology, 2023 Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier permeability, synovial inflammation, hematopoiesis, and embryonic ...
Elena Grebenciucova, Stephen VanHaerents
semanticscholar +1 more source
Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms
Experimental and Molecular Medicine, 2021 Interleukin-6 (IL-6) plays a crucial role in host defense against infection and tissue injuries and is a bioindicator of multiple distinct types of cytokine storms.
Sujin Kang, T. Kishimoto
semanticscholar +1 more source
Interleukin-6: A Novel Target for Cardio-Cerebrovascular Diseases
Frontiers in Pharmacology, 2021 Cardio-Cerebrovascular Disease is a collective term for cardiovascular disease and cerebrovascular disease, being a serious threat to human health. A growing number of studies have proved that the content of inflammatory factors or mediators determines ...
Jiangping Su +7 more
semanticscholar +1 more source
Interleukin‐6 in Covid‐19: A systematic review and meta‐analysis
medRxiv, 2020 Coronaviruses may activate dysregulated host immune responses. As exploratory studies have suggested that interleukin‐6 (IL‐6) levels are elevated in cases of complicated Covid‐19, we undertook a systematic review and meta‐analysis to assess the evidence
E. Coomes, H. Haghbayan
semanticscholar +1 more source
Phenotypic features of interleukin-6 gene polymorphism in the context of formation of addictive pathology [PDF]
, 1998 Search for biomarkers of addictive disorders including molecular-genetic and immunoregulatory characteristics is of relevance. 114 persons with mental and behavioural disorders caused by use of psychoactive substances and 97 conditionally healthy persons
Brokmeier, Heinz-Günter +2 more
core +2 more sources
Correlation Between Interleukin 6 and Interleukin 10 in Acute Myocardial Infarction
Biomolecules & Biomedicine, 2009 The aim of this study was to analyze (i) ratios between pro-inflammatory cytokines interleukin 6 (IL-6), interleukin 1 (IL-1), tumour necrosis factor α (TNF-α) and anti-inflammatory cytokine interleukin 10 (IL-10) in patients with acute myocardial ...
Larisa Dizdarević-Hudić +9 more
doaj +1 more source