Results 41 to 50 of about 555,638 (360)

A qualitative analysis of a A$β$-monomer model with inflammation processes for Alzheimer's disease [PDF]

arXiv, 2022
We introduce and study a new model for the progression of Alzheimer's disease incorporating the interactions of A$\beta$-monomers, oligomers, microglial cells and interleukins with neurons through different mechanisms such as protein polymerization, inflammation processes and neural stress reactions.
arxiv  

A Fast Second-Order Explicit Predictor-Corrector Numerical Technique To Investigating And Predicting The Dynamic Of Cytokine Levels And Human Immune Cells Activation In Response To Gram-Positive Bacteria: Staphylococcus Aureus [PDF]

arXiv, 2023
This paper develops a second-order explicit predictor-corrector numerical approach for solving a mathematical model on the dynamic of cytokine expressions and human immune cell activation in response to the bacterium staphylococcus aureus (S. aureus). The proposed algorithm is at least zero-stable and second-order accurate.
arxiv  

Interleukin-17A and interleukin-23 in morphea

Archives of Medical Science, 2012
Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea.The studies were performed on 41 ...
Anna Olewicz-Gawlik, Aleksandra Dańczak-Pazdrowska, Aleksandra Szewczyk, Wojciech Silny, Marta Molińska-Glura, Ryszard Żaba, Beata Szramka-Pawlak, Paweł Hrycaj, Justyna Gornowicz-Porowska, Michał J. Kowalczyk   +9 more
openaire   +3 more sources

Cytokine levels associated with favorable clinical outcome in the CAPSID randomized trial of convalescent plasma in patients with severe COVID-19

Frontiers in Immunology, 2022
ObjectivesTo determine the profile of cytokines in patients with severe COVID-19 who were enrolled in a trial of COVID-19 convalescent plasma (CCP).MethodsPatients were randomized to receive standard treatment and 3 CCP units or standard treatment alone (
Sixten Körper, Eva Vanessa Schrezenmeier, Eva Vanessa Schrezenmeier, Hector Rincon-Arevalo, Hector Rincon-Arevalo, Beate Grüner, Daniel Zickler, Manfred Weiss, Thomas Wiesmann, Kai Zacharowski, Johannes Kalbhenn, Martin Bentz, Matthias M. Dollinger, Gregor Paul, Philipp M. Lepper, Lucas Ernst, Hinnerk Wulf, Sebastian Zinn, Thomas Appl, Bernd Jahrsdörfer, Markus Rojewski, Ramin Lotfi, Thomas Dörner, Thomas Dörner, Bettina Jungwirth, Erhard Seifried, Daniel Fürst, Hubert Schrezenmeier   +27 more
doaj   +1 more source

Interleukin-1 and Interleukin-6 in Psoriasis

Journal of Investigative Dermatology, 1990
We report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, using a sensitive enzyme-linked immunoabsorbent assay (ELISA) and bio-assay.
Jozef Van Damme, Bakkus Mh, Errol P. Prens, Karin Brakel, Robbert Benner, Klazina. Benne, Theodoor van Joost   +6 more
openaire   +3 more sources

Vertebrate interleukins originated in invertebrates? [PDF]

Invertebrate Survival Journal, 2007
Previous studies have demonstrated that invertebrate immune and neural tissues contain mammalian-like cytokines, which activate specific cellular functions. Therefore, it was of interest to attempt to identify these molecules via Applied Biosystems Human
S Gerber, P Cadet, M Sheehan, G B Stefano, J J Mantione   +4 more
doaj   +1 more source

Interleukins in Platelet Biology: Unraveling the Complex Regulatory Network

Pharmaceuticals
Interleukins, a diverse family of cytokines produced by various cells, play crucial roles in immune responses, immunoregulation, and a wide range of physiological and pathological processes.
Miao Huang, Long Wang, Qianhui Zhang, Ling Zhou, Rui Liao, Anguo Wu, Xinle Wang, Jiesi Luo, Feihong Huang, Wenjun Zou, Jianming Wu   +10 more
doaj   +1 more source

Candidate Molecular Compounds as Potential Indicators for Meibomian Gland Dysfunction

Frontiers in Medicine, 2022
Meibomian gland dysfunction (MGD) is the leading cause of dry eye disease throughout the world. Studies have shown that several molecules in meibum, including but not limited to interleukins, amino acids, cadherins, eicosanoids, carbohydrates, and ...
Kofi Asiedu
doaj   +1 more source

How native state topology affects the folding of Dihydrofolate Reductase and Interleukin-1beta [PDF]

, 2000
The overall structure of the transition state and intermediate ensembles experimentally observed for Dihydrofolate Reductase and Interleukin-1beta can be obtained utilizing simplified models which have almost no energetic frustration. The predictive power of these models suggest that, even for these very large proteins with completely different folding
arxiv   +1 more source

Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review

Tropical Medicine and Infectious Disease
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress ...
A. Al-Qahtani, F. Alhamlan, A. Al-Qahtani   +2 more
semanticscholar   +1 more source