Molecular mechanisms of the regulation of ATPase cycle in striated muscle [PDF]
, 2007 New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements of ...
Charles S. Redwood +2 more
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PLoS GeneticsThe presence of large protein inclusions is a hallmark of neurodegeneration, and yet the precise molecular factors that contribute to their formation remain poorly understood.
Katelyn M Sweeney +15 more
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Synemin Redefined: Multiple Binding Partners Results in Multifunctionality
Frontiers in Cell and Developmental Biology, 2020 Historically synemin has been studied as an intermediate filament protein. However, synemin also binds the type II regulatory (R) subunit α of protein kinase A (PKA) and protein phosphatase type 2A, thus participating in the PKA and phosphoinositide 3 ...
Mary A. Russell
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Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy. [PDF]
, 2015 PurposeTo report potentially pathogenic mutations in the keratin 3 (KRT3) and keratin 12 (KRT12) genes in two individuals with clinically diagnosed Meesmann corneal dystrophy (MECD).MethodsSlit-lamp examination was performed on the probands and available
Aldave, Anthony J +7 more
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High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. [PDF]
, 1983 We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of macrophages spreading onto glass coverslips by both critical-point drying of broken-open cells and ...
Aggeler, J, Takemura, R, Werb, Z
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Intermediate filament linker proteins.
Society of General Physiologists series, 1997 Soc Gen Physiol ...
Fuchs, E. +6 more
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Heterodimeric Associations between Neuronal Intermediate Filament Proteins [PDF]
Journal of Biological Chemistry, 1997 Formation of protein dimers involving alpha-internexin, peripherin, and the neurofilament (NF) proteins NFH, NFM, and NFL was investigated by partial renaturation of various combinations of individually purified subunits in buffered 2 M urea. Oligomers that were formed were resolved by "blue" native electrophoresis (Schägger, H., Cramer, W. A., and von
E S, Athlan, W E, Mushynski
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Hierarchical coexistence of universality and diversity controls robustness and multi-functionality in intermediate filament protein networks [PDF]
, 2007 Proteins constitute the elementary building blocks of a vast variety of biological materials such as cellular protein networks, spider silk or bone, where they create extremely robust, multi-functional materials by self-organization of structures over ...
Markus J. Buehler, Theodor Ackbarow
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Order and disorder in intermediate filament proteins [PDF]
FEBS Letters, 2015 Intermediate filaments (IFs), important components of the cytoskeleton, provide a versatile, tunable network of self‐assembled proteins. IF proteins contain three distinct domains: an α‐helical structured rod domain, flanked by intrinsically disordered head and tail domains.
Kornreich, Micha +4 more
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Distribution, contribution and regulation of nestin+ cells
Journal of Advanced ResearchBackground: Nestin is an intermediate filament first reported in neuroepithelial stem cells. Nestin expression could be found in a variety of tissues throughout all systems of the body, especially during tissue development and tissue regeneration ...
Ziyang Tong, Zi Yin
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