Results 111 to 120 of about 40,471 (297)

Interneuron dysfunction in amyotrophic lateral sclerosis

, 2017
Despite more than a century of research, there is still no cure for amyotrophic lateral sclerosis (ALS) and the only available therapeutic extends survival by mere months.
Clark, RM (15935318)
core   +1 more source

Prefrontal interneuron genes underlie neurobiological processes shared between psychiatric disorders

, 2022
Previous reports on brain co-expression networks, mostly applied to tissue homogenates, have utilized cluster-based strategies for assigning genes to a unique co-expression cluster.
Daniel Weinberger, Gustavo Turecki, Leonardo Sportelli, Giulio Pergola, Corina Nagy   +4 more
core   +1 more source

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy (Kerodon rupestris) and the common marmoset (Callithrix jacchus)

The Anatomical Record, EarlyView.
Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso, Yasmin Pinto Fernandes Albuquerque, Karina Maia Paiva, Rodrigo Freire Oliveira, Nelyane Nayara Martins de Santana, Expedito Silva do Nascimento‐Júnior, Rovena Clara G. J. Engelberth, Jeferson de Souza Cavalcante, Adhil Bhagwandin, Paulo Leonardo Araújo de Góis Morais, José Rodolfo Lopes de Paiva Cavalcanti   +10 more
wiley   +1 more source

Electroconvulsive Therapy for Catatonia in Autistic and Non‐Autistic Patients: An Observational Study on Course, Efficacy, Aggression, and Self‐Injury Outcomes

Autism Research, EarlyView.
ABSTRACT Catatonia occurs disproportionately in autistic individuals and may respond to electroconvulsive therapy (ECT), yet prior reports suggest greater treatment burden in this population. We compared longitudinal ECT utilization, safety, and clinical outcomes between autistic and non‐autistic patients with catatonia.
Joshua Ryan Smith, Maria Bonnee, Sarah Marler, Seri Lim, D. Catherine Fuchs, Rafael Tamargo, Isaac Baldwin, Christopher Maley, Ashley VanHaverbeck, Courtney Hamilton, Timothy Adegoke, Haozheng Xu, Jinyuan Liu, Zachary J. Williams, Jo Ellen Wilson, James Luccarelli   +15 more
wiley   +1 more source

Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex

Frontiers in Neural Circuits, 2007
Neurogliaform cells in the rat elicit combined GABAA and GABAB receptor-mediated postsynaptic responses on cortical pyramidal cells and establish electrical synapses with various interneuron types.
Szabolcs Oláh, Gergely Komlósi, János Szabadics, Csaba Varga, Éva Tóth, Pál Barzó, Gábor Tamás   +6 more
doaj   +1 more source

Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development [PDF]

, 2018
Immature neurons generated by the subpallial MGE tangentially migrate to the cortex where they become parvalbumin-expressing (PV+) and somatostatin (SST+) interneurons.
Lindtner, Susan, Yan Wen, Yanling Wang, Yan You, Zhengang Yang, You, Yan, Qifei Liang, Yang, Zhengang, Liu, Zhidong, Zhejun Xu, Liang, Qifei, Bin Chen, Song Wei, Zhenmeiyu Li, Wen, Yan, Xu, Zhejun, Wei, Song, Li, Zhenmeiyu, Wang, Yanling, Susan Lindtner, Chen, Bin, Tao, Guangxu, Zhidong Liu, Rubenstein, John L, Zhuangzhi Zhang, Zhang, Zhuangzhi, John L Rubenstein, Guangxu Tao   +27 more
core   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Parameters of the PV and SOM interneuron models.

, 2021
Parameters of the PV and SOM interneuron models.
Henning Sprekeler (183138), Richard Naud (129559), Filip Vercruysse (2101237)   +2 more
core   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Multi-dimensional classification of GABAergic interneurons with Bayesian network-modeled label uncertainty

Frontiers in Computational Neuroscience, 2014
Interneuron classification is an important and long-debated topic in neuroscience. A recent study provided a data set of digitally reconstructed interneurons classified by 42 leading neurocientists according to a pragmatic classification scheme composed ...
Bojan eMihaljević, Concha eBielza, Ruth eBenavides-Piccione, Ruth eBenavides-Piccione, Javier eDeFelipe, Javier eDeFelipe, Pedro eLarrañaga   +6 more
doaj   +1 more source