Results 181 to 190 of about 31,667 (251)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Neural Organoid Models as a Platform for Studying Disease Mechanisms in Amyotrophic Lateral Sclerosis

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Amyotrophic lateral sclerosis (ALS) involves widespread cortical pathology beyond the motor cortex. Human‐induced pluripotent stem cell‐derived neural organoids model cortical tissue in vitro and provide a physiologically relevant platform to study disease mechanisms in ALS.
Kristel N. Eigenhuis, Roberto Montoro Ferrer, R. Jeroen Pasterkamp   +2 more
wiley   +1 more source

Social familiarity strengthens neural and vocal responses to conspecific calls in zebra finches. [PDF]

PLoS Comput Biol
Gomez-Guzman CM, Vallentin D, Benichov JI.   +2 more
europepmc   +1 more source

Reduced Mechanical Tactile Stimulation Under Space Microgravity Affects Synaptic Signaling and Contributes to Neuromuscular Aging in Caenorhabditis elegans

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Microgravity (μG) reduces mechanical tactile stimulation in Caenorhabditis elegans, causing neuromuscular decline, altered gene expression, synaptic defects, and accelerated aging phenotypes. The gentle‐touch mechanoreceptor MEC‐4 mediates μG‐induced body length reduction and extracellular matrix gene downregulation.
Atsushi Higashitani, Je‐Hyun Moon, Jong‐In Hwang, Nahoko Higashitani, Toko Hashizume, Ahmad Aisha Abu, Kazuki Ooizumi, Ibuki Sazuka, Yoshimitsu Hashizume, Masumi Umehara, Alfredo V. Alcantara Jr, Ban‐seok Kim, Timothy Etheridge, Nathaniel J. Szewczyk, Takaaki Abe, Jin I. Lee, Akira Higashibata   +16 more
wiley   +1 more source

APP family in inhibitory neurons controls inhibitory recruitment and short-term plasticity in the hippocampus. [PDF]

Mol Brain
Lee SH, Kang J, Zhang C, Bolshakov VY, Shen J.   +4 more
europepmc   +1 more source

Interhemispheric Metabolic Effects of Transcranial Infrared Laser Stimulation of the Prefrontal Cortex

Human Brain Mapping, Volume 47, Issue 9, June 15, 2026.
Unilateral prefrontal TILS reliably increases ipsilateral cytochrome‐c‐oxidase and oxygenated hemoglobin, demonstrating dose‐dependent metabolic efficacy without adverse effects. Contralateral responses are asymmetric: changes emerge later and differ by stimulation side, with stronger right‐hemisphere effects after left‐sided TILS, suggesting ...
Patrick O'Connor, Turner Lime, Douglas W. Barrett, Li‐da Huang, F. Gonzalez‐Lima   +4 more
wiley   +1 more source

Emergence of clustered synapses during the development of a nervous system. [PDF]

BMC Biol
Balshayi Y, Bokman E, Zaslaver A.
europepmc   +1 more source

APOE4 and doxorubicin impair inhibitory interneuron function and homeostatic regulation in the entorhinal cortex. [PDF]

PLoS One
Luo N, Pandit H, Kalra S, Tran E, Mandelblatt J, Vicini S, Rebeck GW.   +6 more
europepmc   +1 more source