Developmentally defined subcircuits in the hippocampus support spatial learning. [PDF]
NeuronHuszár R +6 more
europepmc +1 more source
Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss
Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub +3 more
wiley +1 more source
GABA<sub>A</sub> receptor dysfunction in autism spectrum disorder: molecular mechanisms and therapeutic opportunities. [PDF]
Front PharmacolRagu Varman D +5 more
europepmc +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
Biological Reviews, Volume 101, Issue 5, Page 2408-2426, October 2026.ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
Maternal gut dysbiosis is associated with altered enteric and cortical inhibitory circuit development. [PDF]
Front NeuroanatNakhal MM +11 more
europepmc +1 more source
Glia, Volume 74, Issue 10, October 2026.We used CellChat to infer altered cell–cell communication in Alzheimer's disease Microglia signal to each other via SPP1 in Alzheimer's disease. SPP1‐expressing microglia are present around amyloid‐β plaques. ABSTRACT Microglia play a key role in the pathophysiology of Alzheimer's Disease (AD) and their increased heterogeneity likely affects disease ...
Janssen M. Kotah +7 more
wiley +1 more source
Developmental alcohol exposure: Impacts on medial prefrontal cortex morphology and the excitatory-inhibitory balance. [PDF]
Prog Neuropsychopharmacol Biol PsychiatryCirafesi CK, Karkhanis AN, Diaz MR.
europepmc +1 more source
Glia, Volume 74, Issue 10, October 2026.Bmal1 regulates astrocyte extracellular matrix (ECM) gene expression. Bmal1 deletion in astrocytes disrupts normal circadian rhythms in perineuronal nets (PNN) and reduces PNN content in the hippocampus. In parallel with loss of PNNs, deletion of the core circadian clock gene Bmal1 in astrocytes alters behavior and synaptic function in vivo.
Philip C. Smith +6 more
wiley +1 more source
Selective enrichment of TCF4 in GABAergic neurons during postnatal primate development. [PDF]
Front NeuroanatBurette AC +9 more
europepmc +1 more source
Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States
Glia, Volume 74, Issue 10, October 2026.Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar +3 more
wiley +1 more source