Results 91 to 100 of about 5,857 (224)

Overexpression of Spexin 1 in the Dorsal Habenula Reduces Anxiety in Zebrafish

Frontiers in Neural Circuits, 2019
Spexin (SPX) is an evolutionarily conserved neuropeptide that is expressed in the mammalian brain and peripheral tissue. Two orthologs are present in the teleost, SPX1 and SPX2. SPX1 is involved in reproduction and food intake.
Inyoung Jeong, Eunmi Kim, Jae Young Seong, Hae-Chul Park   +3 more
doaj   +1 more source

Are there predictive pupillometry markers in determining external ventricular device (EVD) weaning failure or success in subarachnoid hemorrhage patients? [PDF]

, 2018
Pupillometers objectively measure constriction (i.e., parasympathetic pathwy) and dilation (i.e., sympathetic pathway) velocities of the pupillary reflex.
Bezner, Tracy, Katyal, Nakul, Nattanmai, Premkumar, Newey, Christopher, Premkumar, Keerthivaas   +4 more
core   +1 more source

Pax6 and Pax7 in the Central Nervous System of Cladistian Fishes: A Comprehensive Expression Analysis

Journal of Comparative Neurology, Volume 533, Issue 4, April 2025.
The Pax6 and Pax7 expression patterns in cladistian fishes showed a high degree of conservation with all vertebrates studied, particularly in the forebrain and midbrain, and some exclusive features, such as the almost total absence of Pax6 in the adult pallium, with the exception of the putative pallial amygdala.
Daniel Lozano, Adrián Chinarro, Lucía Yanguas, Ruth Morona, Nerea Moreno, Jesús M. López   +5 more
wiley   +1 more source

A cell-type-specific circuit of somatostatin neurons in the habenula encodes antidepressant action in male mice

Nature Communications
Major depression is characterized by an array of negative experiences, including hopelessness and anhedonia. We hypothesize that inhibition of negative experiences or aversion may generate antidepressant action.
Lingli Luo, Wei Jing, Yiqing Guo, Dan Liu, Aodi He, Youming Lu   +5 more
doaj   +1 more source

Gpr149 is involved in energy homeostasis in the male mouse [PDF]

PeerJ
GPR149 is an orphan receptor about which little is known. Accordingly, in the present study, we mapped the tissue expression of Gpr149 in mice using three complementary approaches: quantitative PCR, in situ hybridization, and a newly generated Gpr149-Cre
Steven Wyler, Surbhi, Newton Cao, Warda Merchant, Angie Bookout, Laurent Gautron   +5 more
doaj   +2 more sources

Potassium Release From the Habenular Astrocytes Induces Depressive‐Like Behaviors in Mice

Glia, Volume 73, Issue 4, Page 759-772, April 2025.
Main Points Perinatal Dbx1‐expressing prosomere domain is a source of astrocytes in the habenula. Photostimulation of the astrocytes activates neurons in the habenula by increasing extracellular potassium ion leading to the depressive‐like behaviors.
Hidenori Aizawa, Miho Matsumata, Laura Ayaka Noguera Oishi, Fumie Nishimura, Deepa Kamath Kasaragod, Xintong Yao, Wanqin Tan, Tomomi Aida, Kohichi Tanaka   +8 more
wiley   +1 more source

Distribution of glycinergic neurons in the brain of glycine transporter-2 Tg(glyt2:gfp) transgenic adult zebrafish:Relation with brain-spinal descending systems [PDF]

, 2013
We used a Tg(glyt2:gfp) transgenic zebrafish expressing the green fluorescent protein (GFP) under control of the glycine transporter 2 (GLYT2) regulatory sequences to study for the first time the glycinergic neurons in the brain of an adult teleost.
Adrio, Ali, Allain, Aprison, Aprison, Aragón, Becker, Berki, Bowery, Brodin, Buchanan, Campistron, Castro, Castro, Clemente, Curtis, Dale, Edds-Walton, Edds-Walton, Filippi, Finger, Guastella, Higashijima, Higashijima, Higashijima, Holstege, Hossaini, Hunter, Imboden, Johnson, Kaslin, Kimmel, Kinkhabwala, Koyama, Kuscha, Landwehr, Lannoo, Lee, Lee, Lee, Legendre, Liao, Lieberoth, Liu, Liu, Ma, McCormick, McCormick, McLean, Meng, Metcalfe, Moly, Mueller, Mueller, Mueller, Nakayama, Parsons, Pierce, Pourcho, Poyatos, Rampon, Redecker, Reichenberger, Reichenberger, Roberts, Rovsing, Saint Marie, Sassa, Sato, Seitanidou, Smith, Tanaka, Tanaka, Triller, Triller, Uematsu, Valle-Maroto, Van den Pol, Vatine, Villar-Cerviño, Villar-Cerviño, Villar-Cerviño, Walberg, Wannier, Wenthold, Wester, Westerfield, Wullimann, Wullimann, Xue, Yamamoto, Yamamoto, Yang, Young, Yáñez, Zafra, Zafra, Zeilhofer   +97 more
core   +1 more source

DHARANI: A 3D Developing Human‐Brain Atlas Resource to Advance Neuroscience Internationally Integrated Multimodal Imaging and High‐Resolution Histology of the Second Trimester

Journal of Comparative Neurology, Volume 533, Issue 2, February 2025.
ABSTRACT We introduce DHARANI, the first online platform with three‐dimensional (3D) histological reconstructions of the developing human brain from 14 to 24 gestational weeks (GW) across the five fetal brains. DHARANI features 5132 Nissl, hematoxylin and eosin stained, 20 µm coronal and sagittal sections, postmortem MRI, and a neuroanatomical atlas ...
Richa Verma, Mihail Bota, Keerthi Ram, Jaikishan Jayakumar, Rebecca Folkerth, Karthika Pandurangan, Jivitha Jyothi Ramesh, Moitrayee Majumder, Rakshika Raveendran, Reetuparna Nanda, Sivamani K, Amal Dhivahar S, Srinivasa Karthik, Ramdayalan Kumarasami, Suresh S, S. Lata, E. Harish Kumar, Rajeswaran Rangasami, Chitra Srinivasan, Jayaraman Kumutha, Sudha Vasudevan, Koushik Bhat, Chrisline Sam C, Sivathanu Neelakantan, Stephen Savoia, Partha P. Mitra, Jayaraj Joseph, Paul R. Manger, Mohanasankar Sivaprakasam   +28 more
wiley   +1 more source

GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact

Frontiers in Neuroscience, 2019
GPR139, a Gq-coupled receptor that is activated by the essential amino acids L-tryptophan and L-phenylalanine, is predominantly expressed in the brain and pituitary.
Lien Wang, Grace Lee, Chester Kuei, Xiang Yao, Anthony Harrington, Pascal Bonaventure, Timothy W. Lovenberg, Changlu Liu   +7 more
doaj   +1 more source

Novel Mammillary Body Manual Segmentation: Application for Quantitative MRI Analysis of Critically Ill Infants

Clinical Neuroimaging, Volume 2, Issue 1, 2025.
ABSTRACT Background and Purpose Previous qualitative studies have shown that mammillary body (MB) assessment can serve as an early marker of poor long‐term neurodevelopmental outcomes. This study aims to establish a reliable quantitative method for analyzing the surface area, volume, and signal intensity of MB in infancy.
Mackenzie S. Kagan, David Zurakowski, Emi Takahashi, Russell W. Jennings, Dusica Bajic   +4 more
wiley   +1 more source