Results 81 to 90 of about 5,857 (224)

The Brain of the African Wild Dog. VI. The Motor System

Journal of Comparative Neurology, Volume 533, Issue 7, July 2025.
Neurofilament H‐immunostained coronal section through the rostral portion of the hypoglossal nucleus of the African wild dog brain. Note the presence of a distinct fascicle of protoplasmic commissural dendrites between the nuclei. This feature may be related to complex control of the tongue and vocalizations in this socially complex species.
Samson Chengetanai, Adhil Bhagwandin, Mads F. Bertelsen, Therese Hård, Patrick R. Hof, Muhammad A. Spocter, Paul R. Manger   +6 more
wiley   +1 more source

Landmarks for the Location of the Subthalamic Nucleus Using Magnetic Resonance Imaging

Brazilian Neurosurgery, 2017
Deep brain stimulation has become an option for advanced Parkinson's disease treatment since the 1990s, but the first reports are from Benabid's team, a French neurosurgeon, in the 1980s.
Luiza Louza Normanha, Jéssica Rodrigues Borges Leão, Ledismar José Silva   +2 more
doaj   +1 more source

Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex—a relevant mechanism in the pathophysiology and treatment of depression? [PDF]

, 2018
The dorsal diencephalic conduction system connects limbic forebrain structures to monaminergic mesencephalic nuclei via a distinct relay station, the habenular complexes. Both habenular nuclei, the lateral as well as the medial nucleus, are considered to
Bernard, René, Bernstein, Hans-Gert, Laube, Gregor, Veh, Rüdiger W., Weiss, Torsten   +4 more
core   +2 more sources

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

Genetically defined nucleus incertus neurons differ in connectivity and function

eLife
The nucleus incertus (NI), a conserved hindbrain structure implicated in the stress response, arousal, and memory, is a major site for production of the neuropeptide relaxin-3.
Emma D Spikol, Ji Cheng, Michelle Macurak, Abhignya Subedi, Marnie E Halpern   +4 more
doaj   +1 more source

Functional Diversity of Serotonin Neurons in the Dorsal and Median Raphe Nuclei in Emotional Responses

Neuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.
Recent advances challenge the traditional view of serotonin as a uniform neuromodulatory system, revealing the functional diversity of serotonin neurons in raphe nuclei, including the dorsal (DRN) and median raphe nuclei (MRN). This review highlights how distinct serotonergic subpopulations exert opposing effects on emotional regulation, necessitating ...
Yu Ohmura, Kazuki Nagayasu
wiley   +1 more source

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases

MedComm, Volume 6, Issue 5, May 2025.
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie, Yuan Li, Xinyue Wang, Elena Blokhina, Evgeny Krupitsky, Marina Vetrova, Ji Hu, Ti‐Fei Yuan, Jue Chen, Hua Wang, Xiangfang Chen   +10 more
wiley   +1 more source

Chronic Nicotine Cell Specifically Upregulates Functional α4* Nicotinic Receptors: Basis for Both Tolerance in Midbrain and Enhanced Long-Term Potentiation in Perforant Path [PDF]

, 2007
Understanding effects of chronic nicotine requires identifying the neurons and synapses whose responses to nicotine itself, and to endogenous acetylcholine, are altered by continued exposure to the drug.
Collins, Allan C., Deshpande, Purnima, Grady, Sharon R., Huang, Qi, Labarca, Cesar, Lester, Henry A., Lindstrom, Jon M., Marks, Michael J., McClure-Begley, Tristan, McKinney, Sheri, Nashmi, Raad, Whiteaker, Paul, Xiao, Cheng   +12 more
core  

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna, Cioni, Carla, Toni, Mattia, Vaccaro, Rosa   +3 more
core   +2 more sources

Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control

Journal of Neuroendocrinology, Volume 37, Issue 5, May 2025.
Abstract Kisspeptin (KP) signaling in the brain is defined by the anatomical distribution of KP‐producing neurons, their fibers, receptors, and connectivity. Technological advances have prompted a re‐evaluation of these chemoanatomical aspects, originally studied in the early years after the discovery of KP and its receptor Kiss1r.
Limei Zhang, Vito Salvador Hernández, Mario Alberto Zetter, Oscar Rene Hernández‐Pérez, Rafael Hernández‐González, Ignacio Camacho‐Arroyo, Lee E. Eiden, Robert P. Millar   +7 more
wiley   +1 more source