Results 1 to 10 of about 16,625 (164)

DNA methylation status of interspersed repetitive sequences in patients with migraine [PDF]

Journal of International Medical Research, 2023
Objective To analyse the methylation status of the Long Interspersed Nuclear Element-1 (LINE-1) and Short Interspersed Nuclear Element Alu (Alu) of peripheral blood mononuclear cells (PBMCs) from patients with migraine compared with healthy control ...
Nino Kraveishvili, Eka Kvaratskhelia, Sandro Surmava, Merab Kvintradze, Maia Zarandia, Tinatin Gorgiladze, Elene Abzianidze   +6 more
doaj   +4 more sources

DNA Methylation Status of the Interspersed Repetitive Sequences for LINE-1, Alu, HERV-E, and HERV-K in Trabeculectomy Specimens from Glaucoma Eyes [PDF]

Journal of Ophthalmology, 2018
Background/Aims. Epigenetic mechanisms via DNA methylation may be related to glaucoma pathogenesis. This study aimed to determine the global DNA methylation level of the trabeculectomy specimens among patients with different types of glaucoma and normal ...
Sunee Chansangpetch, Sasiprapa Prombhul, Visanee Tantisevi, Pimpayao Sodsai, Anita Manassakorn, Nattiya Hirankarn, Shan C. Lin   +6 more
doaj   +2 more sources

Methylation Status of Alu and LINE-1 Interspersed Repetitive Sequences in Behcet's Disease Patients. [PDF]

Biomed Res Int, 2016
Behcet’s Disease (BD) is a multisystem chronic inflammatory disease. The pathology is believed to involve both genetic susceptibility and environmental factors. Hypomethylation leading to activation of interspersed repetitive sequences (IRSs) such as LINE-1 and Alu contributes to the pathologies of autoimmune diseases and cancer. Herein, the epigenetic
Yüksel Ş, Kucukazman SO, Karataş GS, Ozturk MA, Prombhul S, Hirankarn N.   +5 more
europepmc   +5 more sources

Genome assembly and whole-genome resequencing study of Butuo Black sheep (Ovis aries) [PDF]

Scientific Data
Butuo Black sheep (BBS), an ancient indigenous Chinese breed, has co-evolved with the Yi people's semi-nomadic lifestyle and demonstrated exceptional adaptability to high-altitude migrations.
Changsheng Zhong, Lianting Zhang, Weijia Song, Yingang Guo, Jinwang Liu, Zhangjia Baqian, Jinkang Wang, Ran Li, Jianmin Su   +8 more
doaj   +2 more sources

Interstrand crosslinking oligonucleotides elucidate the effect of metal ions on the methylation status of repetitive DNA elements

Frontiers in Chemistry, 2023
DNA methylation plays an important physiological function in cells, and environmental changes result in fluctuations in DNA methylation levels. Metal ions have become both environmental and health concerns, as they have the potential to disrupt the ...
Shan Liu, Kunihiko Morihiro, Fumika Takeuchi, Yufeng Li, Akimitsu Okamoto   +4 more
doaj   +1 more source

Draft genome of the bluefin tuna blood fluke, Cardicola forsteri.

PLoS ONE, 2022
The blood fluke Cardicola forsteri (Trematoda: Aporocotylidae) is a pathogen of ranched bluefin tuna in Japan and Australia. Genomics of Cardicola spp. have thus far been limited to molecular phylogenetics of select gene sequences.
Lachlan Coff, Andrew J Guy, Bronwyn E Campbell, Barbara F Nowak, Paul A Ramsland, Nathan J Bott   +5 more
doaj   +2 more sources

Genome-Wide Identification and Classification of MicroRNAs Derived from Repetitive Elements [PDF]

Genomics & Informatics, 2014
MicroRNAs (miRNAs) are known for their role in mRNA silencing via interference pathways. Repetitive elements (REs) share several characteristics with endogenous precursor miRNAs.
Jeong-An Gim, Hong-Seok Ha, Kung Ahn, Dae-Soo Kim, Heui-Soo Kim   +4 more
doaj   +1 more source

Retrotransposon mapping in spider monkey genomes of the family Atelidae (Platyrrhini, Primates) shows a high level of LINE-1 amplification

Journal of Biological Research, 2022
To investigate the distribution of LINE-1 repeat sequences, a LINE-1 probe was Fluorescence In Situ Hybridized (FISH) on the chromosomes of Ateles geoffroyi and Ateles fusciceps (Atelidae); a LINE-1 probe was also mapped on Cebuella pygmaea (Cebidae ...
Francesca Dumas, Polina L. Perelman, Larisa Biltueva, Melody Roelke   +3 more
doaj   +1 more source

Losing DNA methylation at repetitive elements and breaking bad

Epigenetics & Chromatin, 2021
Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin formation and gene silencing. It has a fundamental role in preserving genome stability (including chromosome stability) by controlling both gene expression and ...
Xena Giada Pappalardo, Viviana Barra
doaj   +1 more source

Interspersion of repetitive with repetitive sequences in an amphibian, Rana berlandieri [PDF]

Nucleic Acids Research, 1980
When conventional genome arrangement analyses performed on R. berlandieri DNA at a normal (60 degrees C) and a high (75 degrees C) reassociation temperature were compared, an additional interspersion pattern was detected which indicates that different classes of repetitive sequences are closely interspersed with each other.
D E, Graham, K E, Schanke
openaire   +2 more sources