Interspersion of repetitive sequences in rat liver DNA
Biochemical and Biophysical Research Communications, 1975Abstract In rat liver DNA, which contains only 20% repetitive sequences, a close interspersion of repetitive and unique sequences is found in about 35 % of the total DNA. The mean length of repetitive and unique alternating sequences is respectively 230 and 400 base pairs.
Pays, Etienne, Ronsse, A
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Short, interspersed, and repetitive DNA sequences in Spiroplasma species
Plasmid, 1987Small fragments of DNA from an 8-kbp plasmid, pRA1, from a plant pathogenic strain of Spiroplasma citri were shown previously to be present in the chromosomal DNA of at least two species of Spiroplasma. We describe here the shot-gun cloning of chromosomal DNA from S.
I, Nur, D J, LeBlanc, J G, Tully
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Replication time of interspersed repetitive DNA sequences in hamsters
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1986The replication time of 34 hamster genomic DNA segments containing interspersed repeat sequences was determined by probing the cloned segments with nick-translated early- and late-replicating hamster DNA. One-third of these cloned families replicated early, one-third replicated late, and one-third replicated without temporal bias.
G P, Holmquist, L A, Caston
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Short interspersed repetitive sequences as a phylogenetic tool
Molecular Biology, 2009The review is dedicated to one of the most common classes of repetitive elements in eukaryotic genomes: short interspersed elements. Their structure, origin, and functioning in the genome are discussed. The variation and abundance of these neutral genomic markers make them a convenient and reliable tool for phylogenetic analysis.
D. A. Kramerov, N. S. Vasetskii
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Use of interspersed repetitive sequences-PCR products for cDNA selection
Mammalian Genome, 1995In order to increase the efficiency of cDNA selection approaches, we describe the use of interspersed repetitive sequences-PCR (IRS-PCR) products to isolate genes from large-insert genomic clones. IRS-PCR is conducted on total yeast DNA containing a YAC of interest so that there is no need to purify the starting genomic clone.
Villard, M +3 more
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Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences
Physiological Genomics, 2010Interspersed repetitive sequences (IRSs) are a major contributor to genome size and may contribute to cellular functions. IRSs are subdivided according to size and functionally related structures into short interspersed elements, long interspersed elements (LINEs), DNA transposons, and LTR-retrotransposons.
Pornrutsami, Jintaridth +1 more
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General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus
Journal of Molecular Biology, 1973The arrangement of repetitive and non-repetitive sequences was studied in the DNA of Xenopus. Labeled DNA sheared to various fragment lengths was reassociated to C_ot 50 (60 °C, 0.18 m-Na^+) with excess 450 nucleotide fragments of unlabeled DNA, and binding of the labeled DNA to hydroxyapatite was measured.
Davidson, Eric H. +3 more
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Interspersed Repetitive Sequences in Bacterial Genomes
1998Prokaryotic and eukaryotic genomes contain dispersed repetitive sequences separating longer single-copy DNA sequences (Lupski and Weinstock, 1992). Various classes of repeated DNA sequences are present in diverse prokaryotic genomes. Coding sequences, such as ribosomal RNA genes (see Chapter 21) and insertion sequences (see Chapters 4 and 20), may be ...
James Versalovic, James R. Lupski
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The Human Pro-opiomelanocortin Gene: Organization, Sequence, and Interspersion with Repetitive DNA
DNA, 1982The human pro-opiomelanocortin (POMC) gene has been characterized by molecular cloning and DNA sequence analysis. Although this gene codes for several different polypeptide hormones, only a single intron interrupts the protein coding region. The DNA in this intron, and in a second intron found in the region of the gene homologous to the mRNA 5 ...
Whitfield, P., Seeburg, P., Shine, J.
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Interspersion of repetitive and non-repetitive DNA sequences in the sea urchin genome
Cell, 1974Abstract Measurements are reported which lead to the conclusion that repetitive and nonrepetitive sequences are intimately interspersed in the majority of the DNA of the sea urchin, Strongylocentrotus purpuratus. Labeled DNA was sheared to various lengths, reassociated with a great excess of 450 nucleotide-long fragments to cot 20, and the binding of ...
Dale E. Graham +3 more
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