Results 131 to 140 of about 31,985 (192)

The Role of Sex Hormones in Cartilaginous Tissues: A Scoping Review

JOR SPINE, Volume 8, Issue 2, June 2025.
The role of sex hormones within cartilaginous tissues remains poorly understood. To address this, we assembled and summarized the available literature regarding the effects of sex hormones in the intervertebral disc, temporomandibular joint, and articular cartilage.
Jeffrey L. Hutchinson, Amalie J. Hutchinson, Joy Feng, Cheryle A. Séguin   +3 more
wiley   +1 more source

Blockade of IgG Fc receptors reduces pain after intervertebral disc injury. [PDF]

Pharmacol Rep
Shi X, Sahbaie P, Guo TZ, Hsu YM, Kingery WS, Clark JD.   +5 more
europepmc   +1 more source

Prolapsed Intervertebral Disc

International Journal of Clinical Practice, 1955
openaire   +2 more sources

An Extracellular Matrix Hydrogel Restores Disc Volume and Alleviates Axial Hypersensitivity in a Rat Model of Disc‐Associated Pain

JOR SPINE, Volume 8, Issue 2, June 2025.
Degenerated painful discs present with mechanical instability, inflammation, and nerve sprouting, however, patients treated with spinal stabilizing procedures often report pain alleviation indicating spinal mechanics, could be causative in the production of pain.
David J. Lillyman, Evie C. Reddick, Kayla E. Ney, Sydney M. Caparaso, Rebecca A. Wachs   +4 more
wiley   +1 more source

Mitochondrial quality control: the real dawn of intervertebral disc degeneration? [PDF]

J Transl Med
Qiu B, Xie X, Xi Y.
europepmc   +1 more source

In Vivo Measurements Reveal Increased Nucleus Pulposus Lactate and Oxygen Concentrations in a Goat Model of Intervertebral Disc Degeneration

JOR SPINE, Volume 8, Issue 2, June 2025.
Although precise pathophysiological mechanisms remain elusive, perturbations in nutrition that adversely impact the cellular microenvironment of the central nucleus pulposus (NP) are considered key contributors to disc degeneration. In this study, we adapted brain tissue oxygen probes and microdialysis catheters for in situ determination of NP tissue ...
Karthikeyan Rajagopal, Thomas P. Schaer, Kyle D. Meadows, Madeline Boyes, Rachel Hilliard, John C. O'Donnell, George R. Dodge, Dmitriy Petrov, Dawn M. Elliott, Robert L. Mauck, Lachlan J. Smith, Neil R. Malhotra   +11 more
wiley   +1 more source

Upregulated CEMIP promotes intervertebral disc degeneration via AP-1-mediated change in chromatin accessibility. [PDF]

Clin Transl Med
Shu S, Zhang X, Feng Z, Liu Z, Wang K, Li F, Wu Y, Shi B, Qiu Y, Zhu Z, Bao H.   +10 more
europepmc   +1 more source

Causal Relationship Between Gut Microbiota, Blood Metabolites, and Intervertebral Disc Degeneration: A Two‐Step, Two‐Sample Bidirectional Mendelian Randomization Study

JOR SPINE, Volume 8, Issue 2, June 2025.
We have identified several specific gut microbiota that may have an effect on intervertebral disc degeneration, and have found possible blood metabolites that mediate the effects of the gut microbiota on intervertebral disc degeneration. This study provides new insights into the mechanisms by which gut microbes are involved in the development of ...
Yi‐Ping Zheng, Dong‐Lin Yang, Lu‐Yang Wang, Xi‐Zhong Zhu, Xing‐Chen Li, Jin‐Hong Miao, Yu‐Sheng Xu   +6 more
wiley   +1 more source

Impact of traumatic intervertebral disc injury on loss of correction following pedicle screw fixation for thoracolumbar fractures. [PDF]

BMC Musculoskelet Disord
Ge T, Li W, Wu J, Wang Q, Li C, Wang S, Xiong W, Fan J.   +7 more
europepmc   +1 more source

An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disc degeneration. [PDF]

Nat Commun
Liu Y, Chao T, Li Y, Peng P, Ge G, Geng D, Dong L, Wang C.   +7 more
europepmc   +1 more source