Results 121 to 130 of about 25,892 (278)
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.ChREBP transcriptionally regulates PGC‐1α, which enhances the expression of fatty acid oxidation genes, promotes the fatty acid oxidation process, and thereby increases the polarization of anti‐inflammatory microglia, reduces the level of inflammatory factors, and improves pain symptoms.
Ziwei Hu +15 more
wiley +1 more source
Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades [PDF]
, 2020 Stefan Stich +13 more
openalex +1 more source
International Journal of Imaging Systems and Technology, Volume 36, Issue 1, January 2026.ABSTRACT Recent technological advancements may now allow shorter reliable magnetic resonance neurography (MRN) scans of the brachial plexus (BP) even at 1.5 T. The objective of this study was to compare ultra‐fast bilateral coronal 3D T2w TSE STIR (3D‐IR) with unilateral sagittal 2D T2w TSE Dixon (2D‐DX) in terms of image quality, diagnostic ...
Fabio Zecca +7 more
wiley +1 more source
Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications
Small Science, Volume 6, Issue 1, January 2026.Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang +3 more
wiley +1 more source
Hydrogel Microspheres for Biomedical Applications
Small Science, Volume 6, Issue 1, January 2026.Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang +11 more
wiley +1 more source
Small Structures, Volume 7, Issue 1, January 2026.This work presents a novel 3D‐printed gradient scaffold for osteochondral repair. The implant features distinct layers, each designed for a specific therapeutic role: a cartilage layer protects tissue and a bone layer promotes regeneration. In vivo experiments confirm the scaffold's effectiveness, demonstrating its dual ability to maintain chondrocyte ...
Chuan Hu +7 more
wiley +1 more source
Degenerative Disc Disease: A Review of Cell Technologies and Stem Cell Therapy
Iranian Journal of Neurosurgery, 2016 Background & Aim: Low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. Although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration.
Kaveh Haddadi
doaj
Identification of Key Genes and Pathways Associated With Pathogenesis of Intervertebral Disc Degeneration by Integrated miRNA-mRNA Network Analysis [PDF]
, 2021 Tao Lan +5 more
openalex +1 more source
The FEBS Journal, Volume 293, Issue 1, Page 295-317, January 2026.P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren +9 more
wiley +1 more source