Results 121 to 130 of about 38,647 (321)

キカイテキソンショウノテイドノチガイガカルボニルストレスハツゲンニオヨボスエイキョウ [PDF]

open access: yes, 2017
  Low back pain is a significant public health problem worldwide. Intervertebral disc degeneration is most significant known risk factor for low back pain. Yet the mechanisms of degeneration remain relatively unknown.
サイモン タング, 日比野 至
core   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen   +9 more
wiley   +1 more source

Spinal ataxia and computed tomography findings in a Poitou donkey affected with congenital occipitoatlantoaxial malformation

open access: yesEquine Veterinary Education, EarlyView.
Summary A 3‐year‐old Poitou donkey was referred for a computed tomography (CT) examination of the cervical spine due to acute deterioration of spinal ataxia. Neurological assessment revealed restricted neck mobility, hypermetria and circumduction of all limbs, indicating a grade 2 out of 5 ataxia.
M. Mikic   +3 more
wiley   +1 more source

Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment

open access: yesJournal of Orthopaedic Translation
As a permanent state of cell cycle arrest, cellular senescence has become an important factor in aging and age-related diseases. As a central regulator of physiology and pathology associated with cellular senescence, the senescence associated secretory ...
Yang Liu   +3 more
doaj  

Spinal Stenosis: An Emerging Complication of Ageing in People With Haemophilia

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Advances in haemophilia care have brought the challenges of ageing for people with haemophilia (PWH) to the forefront. Age‐related spinal degeneration may result in spinal stenosis; however, the rates in PWH are unknown. We sought to systematically review Irish PWH to address this gap in the current literature.
Claire Kelly   +19 more
wiley   +1 more source

The causality between smoking and intervertebral disc degeneration mediated by IL-1β secreted by macrophage: A Mendelian randomization study

open access: yesHeliyon
There is still a lack of high-level evidence regarding the causal relationship between smoking and intervertebral disc degenerative diseases. This study utilized data from genome wide analysis studies and conducted two-sample Mendelian randomization ...
Zhaopu Han, Yicheng Chen, Xiaojian Ye
doaj  

Study and analysis of the correlation between lumbar spondylolisthesis and Modic changes

open access: yesFrontiers in Surgery
BackgroundThis study aimed to explore the risk factors of Modic changes in lumbar spondylolisthesis.MethodsThe distribution of Modic changes in different types of lumbar spondylolisthesis, degree of spondylolisthesis, and degree of intervertebral disc ...
Guang-qing Li   +3 more
doaj   +1 more source

Intervertebral Disc Degeneration Can Predispose to Anterior Vertebral Fractures in the Thoracolumbar Spine [PDF]

open access: bronze, 2006
Michael A. Adams   +4 more
openalex   +1 more source

Patient positioning on the operating table and patient safety: A systematic review and meta‐analysis

open access: yesJournal of Advanced Nursing, EarlyView.
Abstract Aim To identify occurrence of harmful incidents related to patient positioning on operating table. Design Systematic review and meta‐analysis. Data Sources Eight databases including Ovid, Medline, Embase, CINAHL, the Cochrane Library, Epistemonikos, Scopus, Web of Science and Google Scholar were systematically searched from the inception of ...
Signe Berit Bentsen   +5 more
wiley   +1 more source

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