Results 131 to 140 of about 39,314 (264)

Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain

JOR SPINE, Volume 9, Issue 2, June 2026.
Procrustes analysis was used to match osteophyte‐free lumbar vertebral bodies to lumbar vertebral bodies containing osteophytes. The volume of the reference library bone was subtracted to create an osteophyte model, from which regional osteophyte volumes were calculated.
Clarissa LeVasseur, Sabreen Megherhi, Matthew Mesoros, Gina McKernan, Richard Warwose, William Donaldson, Joon Y. Lee, Gwendolyn Sowa, William Anderst   +8 more
wiley   +1 more source

Intradiscal Cutibacterium acnes Sustains Modic Type 1‐Like Lesions Over Time in a Rat Lumbar Endplate Injury Model

JOR SPINE, Volume 9, Issue 2, June 2026.
Intradiscal C. acnes injection sustained MC1‐like lesions with persistent neutrophil sustenance in an etiology‐specific lumbar MC rat model. This suggests that patients with bacterial MC etiology may persist in painful MC1, highlighting C. acnes and neutrophils as potential targets to promote MC1‐to‐MC2 conversion and improve pain and disability ...
Irina Heggli, Alon Lai, Denise Iliff, Marco D. Burkhard, Niklas Koehne, Harsev Singh, Jonathan J. Huang, Alan C. Seifert, Damien Laudier, Noah Bonnheim, Levon Rodriguez, Timothy D. Jacobsen, James C. Iatridis   +12 more
wiley   +1 more source

Study and analysis of the correlation between lumbar spondylolisthesis and Modic changes

Frontiers in Surgery
BackgroundThis study aimed to explore the risk factors of Modic changes in lumbar spondylolisthesis.MethodsThe distribution of Modic changes in different types of lumbar spondylolisthesis, degree of spondylolisthesis, and degree of intervertebral disc ...
Guang-qing Li, Xiao Kang, Wei Li, Shi-shen Pei   +3 more
doaj   +1 more source

Genotype and Allele Frequencies of Canine Degenerative Myelopathy‐Associated SOD1 Gene Variant in Irish Wolfhound Dogs

Animal Genetics, Volume 57, Issue 3, June 2026.
Yoshihiko Yu, Margret L. Casal
wiley   +1 more source

Serglycin secreted by late-stage nucleus pulposus cells is a biomarker of intervertebral disc degeneration

Nature Communications
Intervertebral disc degeneration is a natural process during aging and a leading cause of lower back pain. Here, we generate a comprehensive atlas of nucleus pulposus cells using single-cell RNA-seq analysis of human nucleus pulposus tissues (three males
Fan Chen, Linchuan Lei, Shunlun Chen, Zhuoyang Zhao, Yuming Huang, Guowei Jiang, Xingyu Guo, Zemin Li, Zhaomin Zheng, Jianru Wang   +9 more
doaj   +1 more source

Finite element model reveals the involvement of cartilage endplate in quasi-static biomechanics of intervertebral disc degeneration

Heliyon
Background and objective: The intrinsic link between the compositional and structural attributes and the biomechanical functionality is evident in intervertebral discs.
Yujun Zhang, Yanli Pan, Xinning Mao, Du He, Liangping Zhang, Wei Cheng, Chengyue Zhu, Hang Zhu, Wei Zhang, HongTing Jin, Hao Pan, Dong Wang   +11 more
doaj   +1 more source

New horizons in spine research: Intervertebral disc repair and regeneration. [PDF]

, 2017
Iatridis, James C, Kandel, Rita, Kang, James, Risbud, Makarand V.   +3 more
core   +2 more sources

Small-molecule suppressors of proteoglycan catabolism in degenerative disc cells [PDF]

, 2015
INTRODUCTION: Proteoglycans (PGs) occupy the predominant extracellular matrix (ECM) components in cartilages and intervertebral discs (IVDs). Large numbers of compositional glycosaminoglycans (GAGs) render PG highly hydrophilic for providing water ...
Chan, D, Cheung, K, Leung, V, Masuda, K, Sun, Y   +4 more
core  

Intervertebral Disc Degeneration [PDF]

The American Journal of Pathology, 2004
François Rannou, Tzong-Shyuan Lee, Rui-Hai Zhou, Jennie Chin, Jeffrey C. Lotz, Marie-Anne Mayoux-Benhamou, Jacques Patrick Barbet, Alain Chevrot, John Y.-J. Shyy   +8 more
openaire   +1 more source

Lifetime Physical Loading and Magnetic Resonance‐Derived Intervertebral Disc Health in Adults With Chronic Low Back Pain: A Cross‐Sectional Study

JOR SPINE, Volume 9, Issue 2, June 2026.
Final multiple linear regression model: heat maps showing Bone‐specific Physical Activity Questionnaire score associations with T2 values in five intervertebral disc (IVD) regions with statistically significant covariates controlled for at individual spinal levels.
Claire L. Samanna, Christopher Neason, Scott D. Tagliaferri, Ulrike H. Mitchell, Michelle Caldwell, Ali Imran, Hana Rae Nez, Daniel L. Belavý, Clint T. Miller, David Scott, Niamh L. Mundell, Paul Buntine, Patrick J. Owen   +12 more
wiley   +1 more source