Results 151 to 160 of about 84,616 (318)

Biomechanical analysis of bone mesoscopic structure and mechanical properties of vertebral endplates of degenerated intervertebral discs in rabbits

Medicine in Novel Technology and Devices
In previous studies of disc degeneration, the structural and mechanical properties of the endplate were often neglected. In this paper, the station legislation was used to construct an animal model of minor trauma disc degeneration, and the mechanism of ...
Bingying Zhao, Yuan Guo, Xushu Zhang, Yibo Zhao, Bin Zhao, Ming Zhang   +5 more
doaj   +1 more source

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration

Current Molecular Biology Reports, 2018
This review aims to highlight recent advances in understanding the genetic basis of intervertebral disc degeneration (IDD). It has been known for some time that IDD is highly heritable.
Sabrina Munir, M. Rade, J. Määttä, M. Freidin, F. Williams   +4 more
semanticscholar   +1 more source

Nondestructive, fatigue cyclic, and ramped cyclic biomechanical testing of surgical techniques for stabilization of the lumbosacral junction in dogs

Veterinary Surgery, EarlyView.
Abstract Objective To compare transarticular screw fixation (TSF), pedicle screw‐rod fixation (PSRF), and screws and polymethylmethacrylate (SPMMA) for stabilization of the canine lumbosacral junction (LSJ). Study design Ex vivo biomechanical study.
Lucas A. Smolders, Raphael Arz, Frank Steffen, Antonio Pozzi, Brian Park   +4 more
wiley   +1 more source

Influence of two consecutive partial lateral corpectomies on passive motion of the canine lumbar spine

Veterinary Surgery, EarlyView.
Abstract Objective To assess the effects of a first and second consecutive partial lateral corpectomy (PLC) on the passive range of motion (ROM) of canine lumbar spinal segments. Study design Controlled, ex vivo biomechanical study. Sample population Adult canine cadaveric spines (n = 10). Methods Ten canine lumbar spinal segments were embedded in cast
Lisa F. Becker, Robin Heilmann, Stefan Schleifenbaum, Stefan Kohl, Thomas Flegel   +4 more
wiley   +1 more source

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

Ecotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang, Zhencong Li, Zhongwei Wang, Kuize Liu, Shengbang Huang, Jinguo Liang, Zhiwen Dai, Weixiong Guo, Chao Mao, Siyuan Chen, Jinsong Wei   +10 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

キカイテキソンショウノテイドノチガイガカルボニルストレスハツゲンニオヨボスエイキョウ [PDF]

, 2017
　 Low back pain is a significant public health problem worldwide. Intervertebral disc degeneration is most significant known risk factor for low back pain. Yet the mechanisms of degeneration remain relatively unknown.
サイモン タング, 日比野 至
core   +1 more source

SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn2+ homeostasis

, 2023
Yu Song, Wen Geng, Dingchao Zhu, Huaizhen Liang, Zhi Du, Bide Tong, Kun Wang, Shuai Li, Yong Gao, Xiaobo Feng, Zhiwei Liao, Rongcheng Mei, Yang Cao   +12 more
openalex   +1 more source

Dropped jaw as a feature of suspected nutritional encephalopathy in a cat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 3‐year‐1‐month‐old female neutered domestic shorthair cat was presented for reluctance to jump over 3 months. Neurological and orthopaedic examinations, laboratory tests and cerebrospinal fluid analysis were unremarkable. Magnetic resonance imaging revealed mild bilateral symmetrical intra‐axial changes in the caudal brainstem.
Eleftheria Skovola, Oliver Williams, Serena Maini, Abbe Crawford   +3 more
wiley   +1 more source

Degenerative relationships in lumbar intervertebral discs and facet joints: an MRI-based comparative study of asymptomatic individuals and patients with chronic and intermittent low back pain

Frontiers in Bioengineering and Biotechnology
Degeneration of intervertebral discs and facet joints are common conditions that are thought to be interrelated. This study aimed to investigate the morphological interplay between disc and facet degeneration, as well as relationships between adjacent ...
Hendrik Schmidt, Sandra Reitmaier, Daishui Yang, Georg Duda, Matthias Pumberger   +4 more
doaj   +1 more source