Results 11 to 20 of about 539,014 (352)

Intestinal Barrier Function in Gluten-Related Disorders [PDF]

Nutrients, 2019
Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Schumann, Michael, Withoff, Sebo   +6 more
core   +5 more sources

Adenosine in Intestinal Epithelial Barrier Function

Cells
At the intestinal front, several lines of defense are in place to resist infection and injury, the mucus layer, gut microbiome and strong epithelial junctions, to name a few. Their collaboration creates a resilient barrier.
Mariya Stepanova, Carol M. Aherne
doaj   +3 more sources

Human Intestinal Barrier Function in Health and Disease

Clinical and Translational Gastroenterology, 2016
The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a tight barrier against the ingress of harmful substances, and ...
J. König, J. Wells, Patrice D Cani, C. Garcia-Rodenas, T. Macdonald, A. Mercenier, Jacqueline Whyte, F. Troost, R. Brummer   +8 more
semanticscholar   +6 more sources

Cathelicidin preserves intestinal barrier function in polymicrobial sepsis. [PDF]

Critical Care, 2020
ObjectivesThe intestinal epithelium compartmentalizes the sterile bloodstream and the commensal bacteria in the gut. Accumulating evidence suggests that this barrier is impaired in sepsis, aggravating systemic inflammation. Previous studies reported that
Chan, Hung, Chan, Matthew TV, Cho, Chi H, Gallo, Richard L, Gin, Tony, Ho, Idy HT, Ho, Jeffery, Hu, Wei, Leung, Czarina CH, Li, Qing, Liang, Yonghao, Ling, Lowell, Liu, Xiaodong, Tse, Gary, Ugwu, Felix N, Wong, Sunny H, Wong, Wai Tat, Wu, William KK, Yau, Johnny CW, Yu, Jun, Zeng, Judeng, Zhang, Lin, Zhang, Yuchen   +22 more
core   +8 more sources

Regulation of Intestinal Barrier Function by Microbial Metabolites [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2021
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that continually shapes host pathophysiological responses. Despite readily available abundant metagenomic data, the functional dynamics of gut microbiota remain to be explored in various health and disease conditions.
S. Ghosh, C. Whitley, B. Haribabu, V. Jala   +3 more
semanticscholar   +4 more sources

Gut microbiota regulates acute myeloid leukaemia via alteration of intestinal barrier function mediated by butyrate

Nature Communications, 2022
The gut microbiota has been linked to many cancers, yet its role in acute myeloid leukaemia (AML) progression remains unclear. Here, we show decreased diversity in the gut microbiota of AML patients or murine models.
Ruiqing Wang, Xinyu Yang, Jinting Liu, Fang Zhong, Chen Zhang, Yuhong Chen, Tao Sun, C. Ji, D. Ma   +8 more
semanticscholar   +1 more source

The mechanism of traditional medicine in alleviating ulcerative colitis: regulating intestinal barrier function

Frontiers in Pharmacology, 2023
Ulcerative colitis (UC) is an idiopathic inflammatory disease mainly affects the large bowel and the rectum. The pathogenesis of this disease has not been fully elucidated, while the disruption of the intestinal barrier function triggered by various ...
Qiuyun Xu, Yuan Yao, Yongchao Liu, Jie Zhang, Liming Mao   +4 more
semanticscholar   +1 more source

Obstructive sleep apnea is related to alterations in fecal microbiome and impaired intestinal barrier function

Scientific Reports, 2023
Obstructive Sleep Apnea (OSA) is related to repeated upper airway collapse, intermittent hypoxia, and intestinal barrier dysfunction. The resulting damage to the intestinal barrier may affect or be affected by the intestinal microbiota.
Qianjun Li, Ting Xu, Chuan Shao, Wenhui Gao, Mingming Wang, Yongquan Dong, Xiumin Wang, Feijie Lu, Dan-qing Li, Huanyu Tan, Yin Jiang, Qinge Xie, Fengbo Cai, Lijie Feng, Taoping Li   +14 more
semanticscholar   +1 more source

Helminths and intestinal barrier function [PDF]

Tissue Barriers, 2017
Approximately one-sixth of the worlds' population is infected with helminths and this class of parasite takes a major toll on domestic livestock. The majority of species of parasitic helminth that infect mammals live in the gut (the only niche for tapeworms) where they contact the hosts' epithelial cells.
Derek M, McKay, Adam, Shute, Fernando, Lopes   +2 more
openaire   +2 more sources

TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function

Toxics, 2023
The intestinal epithelium performs vital functions such as nutrient absorption and acting as an intestinal barrier to maintain the host’s homeostasis. Mycotoxin, which affects the processing and storage of animal feedstuff, is a problematic pollutant in ...
Jung Woong Yoon, Sangsu Shin, JeongWoong Park, Bo Ram Lee, Sang In Lee   +4 more
doaj   +1 more source