Results 41 to 50 of about 788,148 (339)

m5C regulator-mediated modification patterns and tumor microenvironment infiltration characterization in colorectal cancer: One step closer to precision medicine

Frontiers in Immunology, 2022
BackgroundThe RNA modification 5-methylcytosine (m5C) is one of the most prevalent post-transcriptional modifications, with increasing evidence demonstrating its extensive involvement in the tumorigenesis and progression of various cancers.
Baoxiang Chen, Baoxiang Chen, Baoxiang Chen, Yiqing Xi, Jianhong Zhao, Jianhong Zhao, Yuntian Hong, Yuntian Hong, Yuntian Hong, Shunhua Tian, Shunhua Tian, Shunhua Tian, Xiang Zhai, Xiang Zhai, Xiang Zhai, Quanjiao Chen, Xianghai Ren, Xianghai Ren, Xianghai Ren, Lifang Fan, Xiaoyu Xie, Xiaoyu Xie, Xiaoyu Xie, Congqing Jiang, Congqing Jiang, Congqing Jiang   +25 more
doaj   +1 more source

Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation [PDF]

, 2016
Although defects in intestinal barrier function are discussed as a key pathogenic factor in patients with inflammatory bowel diseases (IBD), the molecular pathways driving disease-specific alterations of intestinal epithelial cells (IECs) are largely ...
Alastair J.M. Watson, Arif B. Ekici, Becker, Christoph Becker, Claudia Günther, Cord Brakebusch, Distler, Gionata Fiorino, Heller, Hopkins, Imke Atreya, Kerstin Amann, Lin, Markus F. Neurath, Martin Bergö, Ohkusa, Pastorelli, Pechlivanis, Raja Atreya, Rocío López-Posadas, Silvio Danese, Stefan Tenzer, Stefan Wirtz, Stefania Vetrano, Turcotte, Ulrike Billmeier, Veronika Thonn, Zverina   +27 more
core   +1 more source

Pyridostigmine in pediatric Intestinal pseudo-obstruction. case report of a 2-year old girl and literature review [PDF]

, 2019
Pediatric chronic intestinal pseudo-obstruction is a rare disorder characterized by a severe impairment of gastrointestinal motility leading to intestinal obstruction symptoms in the absence of mechanical causes.
Caló, Girolamo, De Giorgio, Roberto, Di Nardo, Giovanni, Esposito, Francesco, Morlando, Alessia, Parisi, Pasquale, Stanghellini, Vincenzo, Villa, Maria Pia, Viscogliosi, Federica   +8 more
core   +2 more sources

Global, regional and national burden of inflammatory bowel disease in females from 1990 to 2021: an analysis of the global burden of disease study 2021

Frontiers in Global Women's Health
Background & aimsThe global incidence of inflammatory bowel disease (IBD) has markedly increased over past several decades. Gender-specific differences have been observed in the epidemiology, manifestation, and prognosis of IBD.
Jingyi Peng, Jingyi Peng, Yuan Yuan, Yuan Yuan, Jie Zhang, Jie Zhang, Yang Ding, Yang Ding, Xingxing He, Xingxing He   +9 more
doaj   +1 more source

The VirS/VirR two-component system regulates the anaerobic cytotoxicity, intestinal pathogenicity, and enterotoxemic lethality of Clostridium perfringens type C isolate CN3685. [PDF]

, 2011
Clostridium perfringens vegetative cells cause both histotoxic infections (e.g., gas gangrene) and diseases originating in the intestines (e.g., hemorrhagic necrotizing enteritis or lethal enterotoxemia).
Ma, Menglin, McClane, Bruce A, Saputo, Juliann, Uzal, Francisco, Vidal, Jorge   +4 more
core   +2 more sources

Intestinal Stricture in Crohn's Disease [PDF]

Intestinal Research, 2015
Crohn's disease (CD) is a disease with chronic inflammation of unknown etiology involving any part of the gastrointestinal tract. The incidence and prevalence of CD are increasing recently in Asia. Half of the CD patients will have intestinal complications, such as strictures or fistulas, within 20 years after diagnosis.
Chien-Chih Tung, Jau-Min Wong, Shu-Chen Wei, Horng-Yuan Wang, Chen-Wang Chang, I-Lun Shih   +5 more
openaire   +3 more sources

Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]

, 2015
Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor, Capanoglu, Esra, Grootaert, CharlotteLA23002000065127801001998257F7A30E30-F0ED-11E1-A9DE-61C894A0A6B4, Kamiloglu, SenemUGent0001303221268020017844329746706457840000-0003-3902-4360553D4B12-2C77-11E3-8FFE-9F6610BDE39D, Van Camp, JohnLA238010009006420000-0002-6468-6107F4B233EA-F0ED-11E1-A9DE-61C894A0A6B4   +4 more
core   +3 more sources

The impact of small intestinal bacterial overgrowth on the efficacy of fecal microbiota transplantation in patients with chronic constipation

mBio
To investigate the impact of Small Intestinal Bacterial Overgrowth (SIBO) on the efficacy of Fecal Microbiota Transplantation (FMT) in patients with chronic constipation, our research team included 218 patients with chronic constipation treated with FMT.
Le Wang, Yue Xu, Long Li, Bo Yang, Di Zhao, Chen Ye, Zhiliang Lin, Jiaqu Cui, Yunkun Liu, Wanyong Zhu, Ning Li, Hongliang Tian, Qiyi Chen   +12 more
doaj   +1 more source

Metabolism-Associated Molecular Classification of Colorectal Cancer

Frontiers in Oncology, 2020
The high heterogeneity of colorectal cancer (CRC) is the main clinical challenge for individualized therapies. Molecular classification will contribute to drug discovery and personalized management optimizing. Here, we aimed to characterize the molecular
Meng Zhang, Meng Zhang, Hai-zhou Wang, Hai-zhou Wang, Ru-yi Peng, Ru-yi Peng, Fei Xu, Fei Xu, Fan Wang, Fan Wang, Qiu Zhao, Qiu Zhao   +11 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source