PEGylated bacteria restore intestinal mucosal barrier [PDF]
Acta Pharmaceutica Sinica BMenghang Zu, Xue Xia, Bo Xiao
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Th22 cells and the intestinal mucosal barrier. [PDF]
Front Immunol, 2023 T-helper 22 (Th22) cells represent a novel subset of CD4+ T cells that exhibit distinctive characteristics, namely the secretion of IL-22 while abstaining from secreting IL-17 and interferon-γ (IFN-γ).
Chen J, Yao J.
europepmc +5 more sources
Repairing the intestinal mucosal barrier of traditional Chinese medicine for ulcerative colitis: a review [PDF]
Frontiers in Pharmacology, 2023 Damage to the intestinal mucosal barrier play an important role in the pathogenesis of ulcerative colitis (UC). Discovering the key regulators and repairing the disturbed barrier are crucial for preventing and treating UC.
Yichen Zong +5 more
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TSP50 Attenuates DSS‐Induced Colitis by Regulating TGF‐β Signaling Mediated Maintenance of Intestinal Mucosal Barrier Integrity [PDF]
Advanced ScienceThe integrity of the intestinal mucosal barrier is crucial for protecting the intestinal epithelium against invasion by commensal bacteria and pathogens, thereby combating colitis.
Jiawei Li +17 more
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Intestinal Mucosal Barrier Is Regulated by Intestinal Tract Neuro-Immune Interplay [PDF]
Frontiers in Pharmacology, 2021 Inflammatory bowel disease, irritable bowel syndrome and severe central nervous system injury can lead to intestinal mucosal barrier damage, which can cause endotoxin/enterobacteria translocation to induce infection and is closely related to the ...
Xin-yu You +7 more
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The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target
Frontiers in Immunology, 2022 Autoimmune diseases are a series of diseases involving multiple tissues and organs, characterized by the over production of abnormal multiple antibodies.
Jia An +7 more
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Journal of Inflammation, 2022 Background Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D(GSDMD).
Jiping Zhao +6 more
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The role of the Notch signalling pathway in the pathogenesis of ulcerative colitis: from the perspective of intestinal mucosal barrier. [PDF]
Front Med (Lausanne), 2023 Ulcerative colitis is a common digestive disorder worldwide, with increasing incidence in recent years. It is an urgent problem to be solved, as it seriously affects and threatens the health and life of the global population.
Ning H, Liu J, Tan J, Yi M, Lin X.
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Frontiers in MicrobiologyObjectiveThe aim of the study is to investigate the function and mechanism of Zinc Gluconate (ZG) on intestinal mucosal barrier damage in antibiotics and Lipopolysaccharide (LPS)-induced mice.MethodsWe established a composite mouse model by inducing ...
Yongcai Wang +10 more
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Berberine alleviates enterotoxigenic Escherichia coli-induced intestinal mucosal barrier function damage in a piglet model by modulation of the intestinal microbiome. [PDF]
Front NutrIntroduction Enterotoxic Escherichia coli (ETEC) is the main pathogen that causes diarrhea, especially in young children. This disease can lead to substantial morbidity and mortality and is a major global health concern.
Du M +9 more
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