Maintenance of intestinal homeostasis by mucosal barriers [PDF]
Inflammation and Regeneration, 2018 Background The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by intestinal epithelial cells make it possible to maintain the symbiotic relationship ...
Ryu Okumura, Kiyoshi Takeda
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Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice [PDF]
Frontiers in NeuroscienceBackgroundGut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut ...
Ning Ding +4 more
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Regulatory Role of IGF2BP2 in Intestinal Mucosal Barrier Dysfunction in Ulcerative Colitis [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: Ulcerative colitis (UC), an idiopathic and chronic inflammatory disease, primarily targets the mucosal lining of the colon. This research endeavors to reveal the mechanism of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2 ...
Ruifan Li, Bin Gu, Anli Lv
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Frontiers in Cellular and Infection Microbiology, 2022 Recent studies have revealed that the effect of intestinal microecological disorders on organismal physiology is not limited to the digestive system, which provides new perspectives for microecological studies and new ideas for clinical diagnosis and ...
Junfeng Guo +8 more
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Zhuanggu Shubi ointment mediated the characteristic bacteria-intestinal mucosal barrier-bone metabolism axis to intervene in postmenopausal osteoporosis [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundZhuanggu Shubi ointment (ZGSBG) has good efficacy in postmenopausal osteoporosis (PMO), but the mechanism of efficacy involving gut microecology has not been elucidated.ObjectiveThis study investigated the mechanism of ZGSBG in regulating gut ...
Xiaoya Li +16 more
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Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice [PDF]
Frontiers in MicrobiologyBackgroundTo establish and evaluate an IBS-D mouse model with Spleen-Kidney Yang Deficiency, explore the microecological mechanisms of IBS-D, and provide experimental evidence for the clinical diagnosis and treatment of IBS-D with Spleen-Kidney Yang ...
Liwen Li +7 more
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Intestinal epithelial barrier and mucosal immunity
Cellular and Molecular Life Sciences, 2005 Intestinal mucosa integrates primary digestive functions with immune functions such as pathogen surveillance, antigen transport and induction of mucosal immunity and tolerance. Intestinal adaptive immunity is elicited in organized mucosa-associated lymphoid tissue (O-MALT) that is composed of antigen-presenting cells and lymphocytes and achieved by ...
C. A. Müller +2 more
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Intestinal mucosal barrier: a potential target for traditional Chinese medicine in the treatment of cardiovascular diseases [PDF]
Frontiers in PharmacologyCardiovascular disease (CVD) is a serious public health problem, and among non-communicable diseases, CVD is now the leading cause of mortality and morbidity worldwide.
Jiahui Liu +6 more
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Progress in Mycotoxins Affecting Intestinal Mucosal Barrier Function [PDF]
International Journal of Molecular Sciences, 2019 Mycotoxins, which are widely found in feed ingredients and human food, can exert harmful effects on animals and pose a serious threat to human health. As the first barrier against external pollutants, the intestinal mucosa is protected by a mechanical ...
Z. Ren +6 more
semanticscholar +3 more sources
Role of polyamines in intestinal mucosal barrier function. [PDF]
Semin ImmunopatholThe intestinal epithelium is a rapidly self-renewing tissue; the rapid turnover prevents the invasion of pathogens and harmful components from the intestinal lumen, preventing inflammation and infectious diseases. Intestinal epithelial barrier function depends on the epithelial cell proliferation and junctions, as well as the state of the immune system
Nakamura A, Matsumoto M.
europepmc +3 more sources