Results 61 to 70 of about 215,029 (331)

Intestinal mucosal barrier in functional constipation: Dose it change?

World Journal of Clinical Cases, 2022
BACKGROUND The intestinal mucosal barrier is the first line of defense against numerous harmful substances, and it contributes to the maintenance of intestinal homeostasis.
Jun-Ke Wang, Wei Wei, Dongyan Zhao, Hui-fen Wang, Yan-li Zhang, Jie-Ping Lei, Shu-kun Yao   +6 more
semanticscholar   +1 more source

Modulation of Gut Barrier Functions in Ulcerative Colitis by Hyaluronic Acid System

Advanced Science, 2022
The active stages of intestinal inflammation and the pathogenesis of ulcerative colitis are associated with superficial mucosal damage and intermittent wounding that leads to epithelial barrier defects and increased permeability. The standard therapeutic
Niranjan G. Kotla, Isma Liza Mohd Isa, Swetha Rasala, Secil Demir, Rajbir Singh, Becca V. Baby, Samantha K. Swamy, Peter Dockery, Venkatakrishna R. Jala, Yury Rochev, Abhay Pandit   +10 more
doaj   +1 more source

Krill oil, vitamin D and Lactobacillus reuteri cooperate to reduce gut inflammation [PDF]

, 2018
Current research into original therapies to treat intestinal inflammation is focusing on no-drug therapies. KLD is a mixture of krill oil (KO), probiotic Lactobacillus reuteri (LR), and vitamin D (VitD3).
Cesi, V., Colantoni, E., Costanzo, M., Cucchiara, S., Leter, B., Negroni, A., Palone, F., Pierdomenico, M., Stronati, L., Vitali, R.   +9 more
core   +1 more source

TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica. [PDF]

, 2013
Our gastrointestinal tract is a portal of entry for a number of bacteria and viruses. Thus, this tissue must develop ways to induce antigen-specific T cell and antibody responses quickly.
DePaolo, R William, Kamdar, K, Karpus, WJ, Khakpour, S, Sugiura, Y, Young, G   +5 more
core   +1 more source

Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis

Bioengineered, 2022
Intestinal barrier dysfunction is inflammatory bowel disease’s hallmark. Berberine (BBR) has manifested its anti-inflammatory properties in colitis.
Xun Zhao, D. Cui, Wen-qiang Yuan, Chen Chen, Qi Liu   +4 more
semanticscholar   +1 more source

Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut

Mediators of Inflammation, 2015
The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting the role of a disturbed interaction between the gut and the intestinal microbiota.
Andrea Michielan, Renata D’Incà
doaj   +1 more source

Lactobacillus reuteri Promotes Intestinal Development and Regulates Mucosal Immune Function in Newborn Piglets

Frontiers in Veterinary Science, 2020
Intestinal microbiota is necessary for the guarantee of intestinal mucosal barrier. However, the detailed effect of probiotics on porcine intestinal development, especially in the early life, is still unclear.
Minjuan Wang, Haiqin Wu, Linhao Lu, Lan Jiang, Qinghua Yu   +4 more
doaj   +1 more source

Protein hydrolysates from animal source food earthworm protect against dextran sulfate sodium (DSS)-induced intestinal barrier injury

Food Science and Human Wellness
The intestinal barrier is crucial for homeostasis. This study aimed to investigate the protective effects of earthworm protein hydrolysates (EWPH) on the intestinal mucosal barrier and elucidate the underlying mechanisms.
Jie Pan, Hui Zhao, Liming Jia, Jinghua Jia, Jingning Jia, Yuhui Li, Qi Tang, Feiya Jiang, Liang Bai, Meiyan Wang, Yufeng Li, Zheng Wang   +11 more
doaj   +1 more source

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ, Dandekar, S, Gaulke, CA, Glavan, TW, Goulart, LR, Hirao, LA, Jiang, G, Raffatellu, M, Sankaran-Walters, S, Santos Rocha, C   +9 more
core   +2 more sources

Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis

Frontiers in Cell and Developmental Biology, 2020
Intestinal epithelial barrier is critical for the maintenance of normal gut homeostasis and disruption of this barrier may trigger or exaggerate mucosal inflammation.
Susana Lechuga, Nayden G. Naydenov, Alex Feygin, Michael Cruise, James M. Ervasti, Andrei I. Ivanov   +5 more
doaj   +1 more source