Results 41 to 50 of about 657,043 (287)

Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer [PDF]

Scientific Reports, 2018
AbstractThe human intestine retains a complex microbial ecosystem, which performs crucial functions that impact on host health. Several studies have indicated that intestinal dysbiosis may impact on the establishment of life-threatening intestinal diseases such as colorectal cancer. An adenomatous polyp is the result of abnormal tissue growth, which is
Mangifesta, Marta, Mancabelli, Leonardo, Milani, Christian, Gaiani, Federica, de’Angelis, Nicola, de’Angelis, Gian Luigi, van Sinderen, Douwe, Ventura, Marco, Turroni, Francesca   +8 more
openaire   +4 more sources

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L., P. J. Cooper, Zaph, C, Cooper, P. J., C. Zaph, Cooper, PJ, Harris, NL, Zaph, C., Cooper, Philip, N. L. Harris   +9 more
core   +1 more source

Protopine Alleviates Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Regulating Intestinal Microbiota

Molecules, 2023
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD), and its pathogenesis is related to intestinal mucosal barrier damage and gut microbiota imbalance. Protopine (PRO), an isoquinoline alkaloid, is one of the main anti-inflammatory ingredients
Meishan Yue, Jialu Huang, Xiaolan Ma, Peng Huang, Yisong Liu, Jianguo Zeng   +5 more
doaj   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Verstegen, M.W.A., Metzler-Zebeli, B.U., Mosenthin, R.   +3 more
core   +1 more source

Molecular characterisation of selected gastrointestinal microbiota in South African HIV-positive patients during HAART [PDF]

, 2012
Includes bibliographical references.Progression of the HIV disease is characterised by a massive depletion of CD4+ T cells and it has been shown that patients living with a more advanced HIV infection have a higher risk of developing diarrhoea due to the
Du Plessis, Sarah Jane
core   +1 more source

Acetylation: a critical factor in maintaining intestinal inflammation? [PDF]

, 2010
PhDIn inflammatory bowel disease (IBD), both chronic pro-inflammatory pathways and failure of anti-inflammatory (healing) mechanisms sustain disease. The two major anti-inflammatory gut cytokines are transforming growth factor (TGF)-β and interleukin (IL)
Epstein, Jenny
core   +4 more sources

Gut Microbiota Signatures in Tumor, Para-Cancerous, Normal Mucosa, and Feces in Colorectal Cancer Patients

Frontiers in Cell and Developmental Biology, 2022
Background: Association studies have linked microbiome alterations with colorectal cancer (CRC). However, differences in tumor, para-cancerous, normal mucosal, and fecal microbiota remain to be strengthened.Methods: We performed a study on the ...
Yanmin Li, Hong Cao, Bojian Fei, Qizhong Gao, Wanya Yi, Weifeng Han, Chuanqing Bao, Jianmin Xu, Wei Zhao, Feng Zhang, Feng Zhang   +10 more
doaj   +1 more source

Establishment of normal gut microbiota is compromised under excessive hygiene conditions [PDF]

, 2011
Peer ...
Stokes, C.R., Schmidt, B, Gill, B.P., Schmidt, B., John R Pluske, Imke E. Mulder, Lewis, M, Kelly, D., Aminov, Rustam, Bhupinder P Gill, Gill, Bhupinder P, Bailey, Mick, Musk, Corran C, Pluske John R., Aminov, Rustam I, Bailey, M., Lewis Marie, Mick Bailey, Musk Corran C., Bailey Mick, Rustam I. Aminov, Stokes, CR, Stokes, Christopher, Musk, Corran, Marie Lewis, Mulder Imke E., Rustam I Aminov, Christopher R Stokes, Kelly, Denise, Pluske, JR, Mulder, Imke E, Stokes, Christopher R, Aminov, R I, Mulder, Imke, Bettina Schmidt, Stokes Christopher R., John R. Pluske, Christopher R. Stokes, Prosser, James I, Plusk, John, Musk C, C, Prosser, James, Gill Bhupinder P., Gill, Bhupinder, Kelly Denise, Lewis, Marie, Bailey, M, Musk, C.C., Lewis, M., Schmidt Bettina, Mulder, I E, Pluske, John R, Mulder, I.E., Prosser, JI, Aminov, R.I., James I Prosser, Pluske, J.R., Kelly, D, Corran C Musk, Imke E Mulder, Prosser James I., Corran C. Musk, Gill, BP, Schmidt, Bettina, James I. Prosser, Aminov Rustam I., Bhupinder P. Gill, Prosser, J.I., Denise Kelly   +68 more
core   +1 more source

Salmonella transiently reside in luminal neutrophils in the inflamed gut. [PDF]

, 2012
Enteric pathogens need to grow efficiently in the gut lumen in order to cause disease and ensure transmission. The interior of the gut forms a complex environment comprising the mucosal surface area and the inner gut lumen with epithelial cell debris and
Mathias Heikenwalder (79126), Patrick Kaiser, Schubert Sören, Stecher, Bärbel, Wieser, Andreas, Kaiser, Patrick, Jette Lengefeld (172749), Schubert, Sören, Stecher, B., Andreas Wieser, Sören Schubert, Loetscher, Yvonne, Stecher Bärbel, Patrick Kaiser (172750), Wolf-Dietrich Hardt, Heikenwalder, Mathias, Lengefeld, J., Bärbel Stecher (78807), Jette Lengefeld, Schubert, S., Andreas Wieser (172747), Wieser Andreas, Loetscher, Y., Loetscher Yvonne, Wolf-Dietrich Hardt (46235), Lengefeld Jette, Heikenwälder, M., Yvonne Loetscher, Kaiser Patrick, Hardt Wolf-Dietrich, Wieser, A., Kaiser, P., Sören Schubert (172752), Bärbel Stecher, Heikenwalder Mathias, Hardt, W.D., Mathias Heikenwalder, Lengefeld, Jette, Hardt, Wolf-Dietrich; id_orcid, Yvonne Loetscher (172745), Hardt, Wolf-Dietrich   +40 more
core   +2 more sources

The Role of Intestinal Microbiota in the Development and Severity of Chemotherapy-Induced Mucositis

PLoS Pathogens, 2010
Mucositis, also referred to as mucosal barrier injury, is one of the most debilitating side effects of radiotherapy and chemotherapy treatment. Clinically, mucositis is associated with pain, bacteremia, and malnutrition. Furthermore, mucositis is a frequent reason to postpone chemotherapy treatment, ultimately leading towards a higher mortality in ...
van Vliet, Michel J., Harmsen, Hermie J. M., de Bont, Eveline S. J. M., Tissing, Wim J. E.   +3 more
openaire   +5 more sources