Results 31 to 40 of about 657,043 (287)

The impact of aging on intestinal mucosal immune function and clinical applications

Frontiers in Immunology, 2022
Immune cells and immune molecules in the intestinal mucosa participate in innate and adaptive immunity to maintain local and systematic homeostasis. With aging, intestinal mucosal immune dysfunction will promote the emergence of age-associated diseases ...
Han Zheng, Chi Zhang, Qianqian Wang, Shuyan Feng, Yi Fang, Shuo Zhang   +5 more
doaj   +1 more source

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation [PDF]

, 2015
The authors acknowledge the support of the Biotechnology and Biological Sciences Research Council (BBSRC), this research was partly funded by the BBSRC Institute Strategic Programme for The Gut Health and Food Safety (BB/J004529/1) and by the BB/L008602 ...
Vos, W.M., de, Hardy-Goddard, Jemma, Crost, Emmanuelle H., de Vos, Willem M., Gall, G., Le, Taylor, Garry L., Walshaw, J., Tailford, L.E., Crost, E.H., Taylor, G.L., Juge, N., Owen, C.D., Tailford, Louise E., Owen, C. David, Le Gall, G., Le Gall, Gwenaelle, Hardy-Goddard, J., Juge, Nathalie, Walshaw, John, de Vos, W.M.   +19 more
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Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals [PDF]

Scientific Reports, 2019
Abstract Gut mucosal microbes evolved closest to the host, developing specialized local communities. There is, however, insufficient knowledge of these communities as most studies have employed sequencing technologies to investigate faecal microbiota only. This work used shotgun metagenomics of mucosal biopsies to
Vaga, Stefania, Lee, Sunjae, Ji, Boyang, Andreasson, Anna, Talley, Nicholas J, Agréus, Lars, Bidkhori, Gholamreza, Kovatcheva-Datchary, Petia, Park, Junseok, Lee, Doheon, Proctor, Gordon, Ehrlich, Dusko, Nielsen, Jens, Engstrand, Lars, Shoaie, Saeed   +14 more
openaire   +5 more sources

Research progress on the relationship between intestinal microecology and intestinal bowel disease

Animal Models and Experimental Medicine, 2022
Intestinal microecology is the main component of human microecology. Intestinal microecology consists of intestinal microbiota, intestinal epithelial cells, and intestinal mucosal immune system. These components are interdependent and establish a complex
Qianhui Fu, Tianyuan Song, Xiaoqin Ma, Jian Cui   +3 more
doaj   +1 more source

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. [PDF]

, 2012
Relapsing C. difficile disease in humans is linked to a pathological imbalance within the intestinal microbiota, termed dysbiosis, which remains poorly understood. We show that mice infected with epidemic C.
Parkhill Julian, Duncan Sylvia H., Deakin, Laura J., Thomas R. Connor (125272), Schreiber Fernanda, Brandt, Cordelia, Pickard Derek J., Flint, Harry J, Harry J. Flint (125298), Parkhill, J, Flint, Harry James, Trevor D. Lawley (125265), Simon Clare, Roland Rad (125284), David Goulding (125280), Julian Parkhill (30393), Claire Raisen (125275), Schreiber, F, Clare Simon, Taane G Clark, Deakin Laura J., Connor Thomas R., Taane G. Clark (106263), Clark, Taane G., Gordon Dougan, Duncan, SH, Sylvia H. Duncan (125296), Stares, Mark D., Raisen Claire, Roland Rad, Trevor D Lawley, Rad, Roland, Derek J. Pickard (125293), Sylvia H Duncan, Walker Alan W., Harry J Flint, Goulding David, Rad, R, Derek J Pickard, Deakin, LJ, Schreiber, Fernanda, Clark, Taane G, Clark, TG, Rad Roland, Walker, Alan W, Flint Harry J., Goulding, David, Alan W. Walker (50247), Raisen, C, Stares, MD, Pickard, Derek J, Flint, Harry J., Lawley, Trevor D, Deakin, Laura J, Connor, Thomas R, Claire Raisen, Brandt, C, Walker, AW, Mark D Stares, Walker, Alan W., Duncan, Sylvia H, Dougan Gordon, Connor, Thomas Richard, Clare, Simon, Pickard, Derek J., Laura J Deakin, Fernanda Schreiber, Fernanda Schreiber (85280), Lawley, TD, Clare, S, Julian Parkhill, Alan W Walker, David Goulding, Lawley, Trevor D., Raisen, Claire, Mark D. Stares (125271), Cordelia Brandt (125287), Laura J. Deakin (125290), Brandt Cordelia, Dougan, Gordon, Pickard, DJ, Duncan, Sylvia H., Parkhill, Julian, Simon Clare (125268), Clark Taane G., Flint, HJ, Gordon Dougan (30395), Thomas R Connor, Stares Mark D., Stares, Mark D, Goulding, D, Cordelia Brandt, Connor, TR, Dougan, G, Lawley Trevor D.   +94 more
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The Research Progress on Intestinal Stem Cells and Its Relationship with Intestinal Microbiota

Frontiers in Immunology, 2017
The intestine is home to trillions of microorganisms, and the vast diversity within this gut microbiota exists in a balanced state to protect the intestinal mucosal barrier.
Qihang Hou, Lulu Ye, Lulu Huang, Qinghua Yu   +3 more
doaj   +1 more source

Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians [PDF]

, 2010
BACKGROUND: Age-related physiological changes in the gastrointestinal tract, as well as modifications in lifestyle, nutritional behaviour, and functionality of the host immune system, inevitably affect the gut microbiota, resulting in a greater ...
Nylund Lotta, Ostan, Rita, Janne Nikkïla, Elisa Pini, Elena Biagi, Rita Ostan, Daniela Monti, Pini Elisa, Satokari, Reetta, Satokari, R.M., Candela, Marco, Nylund L., Nikkilä, Janne Tapio, Nylund, Lotta, de Vos, W.M., Candela Marco, Franceschi Claudio, Willem De Vos, De Vos Willem, Brigidi, Patrizia, Nikkila J., Franceschi, C., Monti, Daniela, Marco Candela, Reetta Satokari, Bucci Laura, Vos, W.M., de, Candela, M., Pini, E., Monti, D., Pini, Elisa, Nikkïla, J., Bucci, Laura, Satokari R., Lotta Nylund, Nikkïla Janne, Satokari Reetta, Monti D., Franceschi, Claudio, Patrizia Brigidi, De Vos W., Biagi, E., Monti Daniela, Biagi Elena, Ostan Rita, Ostan, R., De Vos, Willem, Bucci, L., Laura Bucci, Brigidi, P., Nylund, L., Claudio Franceschi, Brigidi Patrizia, Biagi, Elena   +53 more
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Characteristics and early development of intestinal microbiota in piglets

Siliao yanjiu, 2022
There are dense, dynamic and highly complex microbial communities in pig intestine. Intestinal microbiota plays an important role in promoting intestinal maturation, regulating the immune system, enhancing the health and growth performance of host ...
ZHAO Huai-bao
doaj  

Maintenance of intestinal homeostasis by mucosal barriers

Inflammation and Regeneration, 2018
Background The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by intestinal epithelial cells make it possible to maintain the symbiotic relationship ...
Ryu Okumura, Kiyoshi Takeda
doaj   +1 more source

Alternations of Gastric Microbiota with Mucosal Atrophy and Intestinal Metaplasia [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2020
Atrophic gastritis (AG) and intestinal metaplasia (IM) are regarded as precancerous lesions of gastric cancer. Helicobacter pylori (H. pylori) infection is a major cause of AG and IM. Although stomach is a hostile environment for most bacteria, increased microbial diversity with the predominance of Proteobacteria and Actinobacteria is frequently ...
openaire   +2 more sources