Results 11 to 20 of about 657,043 (287)
Microorganisms, 2019 Host health depends on the intestinal homeostasis between the innate/adaptive immune system and the microbiome. Numerous studies suggest that gut microbiota are constantly monitored by the host mucosal immune system, and any slight disturbance in the ...
Bei Yue +5 more
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An insight into intestinal mucosal microbiota disruption after stroke. [PDF]
Sci Rep, 2018 AbstractRecent work from our laboratory has provided evidence that indicates selective bacterial translocation from the host gut microbiota to peripheral tissues (i.e. lung) plays a key role in the development of post-stroke infections. Despite this, it is currently unknown whether mucosal bacteria that live on and interact closely with the host ...
Stanley D, Moore RJ, Wong CHY.
europepmc +6 more sources
Interplay of intestinal microbiota and mucosal immunity in inflammatory bowel disease: a relationship of frenemies [PDF]
Therapeutic Advances in Gastroenterology, 2020 Inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn’s disease, are chronic inflammatory disorders of the gastrointestinal tract. With in-depth studies on the mechanisms of the initiation and development of IBD, increasing lines of ...
Huimin Chen, Hongfen Li, Zhanju Liu
doaj +3 more sources
Gut Microbiota Modulation on Intestinal Mucosal Adaptive Immunity [PDF]
Journal of Immunology Research, 2019 The mammalian intestine harbors a remarkable number of microbes and their components and metabolites, which are fundamental for the instigation and development of the host immune system. The intestinal innate and adaptive immunity coordinate and interact with the symbionts contributing to the intestinal homeostasis through establishment of a mutually ...
Li Wang, Limeng Zhu, Song Qin
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Involvement of intestinal mucosal microbiota in adenine-induced liver function injury. [PDF]
3 BiotechAdenine is frequently utilized as a model medication for chronic renal disease. Adenine can affect organs other than the kidneys, including the heart and the intestine. The liver is a vital organ involved in the in vivo metabolism of adenine. Adenine may negatively impact liver function.
Fang L, Shen J, Wu Y, Tan Z.
europepmc +4 more sources
Immune Responses to the Microbiota at the Intestinal Mucosal Surface [PDF]
Immunity, 2009 The mammalian intestinal mucosal surface is continuously exposed to a complex and dynamic community of microorganisms. These microbes establish symbiotic relationships with their hosts, making important contributions to metabolism and digestive efficiency.
Duerkop, Breck A. +2 more
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Impact of the Intestinal Microbiota on the Development of Mucosal Defense [PDF]
Clinical Infectious Diseases, 2008 The gastrointestinal tract is a dynamic ecosystem composed of an organized matrix of host eukaryotic cells, including a fully functional immune system, and numerous microbial habitats normally colonized by a diverse array of microbes. Recent analyses of the gastrointestinal microbiota by use of molecular-based methods indicate that bacterial ...
H Rex, Gaskins +3 more
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The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation [PDF]
Cells, 2020 Alterations of the gut microbiota may cause dysregulated mucosal immune responses leading to the onset of inflammatory bowel diseases (IBD) in genetically susceptible hosts. Restoring immune homeostasis through the normalization of the gut microbiota is now considered a valuable therapeutic approach to treat IBD patients.
Amoroso C +5 more
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Intestinal epithelial cells: at the interface of the microbiota and mucosal immunity [PDF]
Immunology, 2019 SummaryThe intestinal epithelium forms a barrier between the microbiota and the rest of the body. In addition, beyond acting as a physical barrier, the function of intestinal epithelial cells (IECs) in sensing and responding to microbial signals is increasingly appreciated and likely has numerous implications for the vast network of immune cells within
Soderholm, Amelia T +1 more
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Nod2: a key regulator linking microbiota to intestinal mucosal immunity [PDF]
Journal of Molecular Medicine, 2011 The human intestine harbors a large number of bacteria that are constantly interacting with the intestinal immune system, eliciting non-pathological basal level immune responses. Increasing evidence points to dysbiosis of microbiota in the intestine as an underlying factor in inflammatory bowel disease susceptibility. Loss-of-function mutations in NOD2
Amlan, Biswas +2 more
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