Results 71 to 80 of about 657,043 (287)

Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice

Frontiers in Neuroscience
BackgroundGut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut ...
Ning Ding, Xin Hao, Yue Zhang, Yanxiang Zhang, Zhigang Li   +4 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Influence of consumption of unsaturated alginate oligosaccharides on the gut microbiota and the intestinal mucosal immunity homeostasis in immunocompromised mice

Carbohydrate Polymer Technologies and Applications
Despite the well-known health benefits of unsaturated alginate oligosaccharides (UAOS), limited information exists on how they regulate the gut microbiota and intestinal mucosal immunity.
Zhaopeng Shen, Hua Yin, Lu Sun, Lu Chen, Jiandong Li, Xin Zhang, Mingyong Zeng, Xiaolu Jiang, Junhong Yu   +8 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Wuling powder ameliorates diarrhea-predominant irritable bowel syndrome in mice by modulating gut mucosal microbiota and alleviating intestinal inflammation

Frontiers in Cellular and Infection Microbiology
ObjectivesWuling powder has been widely used for the clinical treatment of IBS-D, but the microecological mechanism has not been found. This study aimed to investigate the regulatory effect of Wuling powder on intestinal mucosal microbiota in mice with ...
Qianghong Tian, Donglin Yu, Junxi Shen, Leyao Fang, Ying Cai   +4 more
doaj   +1 more source

Spatial heterogeneity and co-occurrence patterns of human mucosal-associated intestinal microbiota [PDF]

The ISME Journal, 2013
Abstract Human gut microbiota shows high inter-subject variations, but the actual spatial distribution and co-occurrence patterns of gut mucosa microbiota that occur within a healthy human instestinal tract remain poorly understood. In this study, we illustrated a model of this mucosa bacterial communities’ biogeography, based on the ...
Zhigang, Zhang, Jiawei, Geng, Xiaodan, Tang, Hong, Fan, Jinchao, Xu, Xiujun, Wen, Zhanshan Sam, Ma, Peng, Shi   +7 more
openaire   +2 more sources

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Gut inflammation in chronic fatigue syndrome

Nutrition & Metabolism, 2010
Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS patients complain of gut dysfunction.
Kirchgessner Annette, Lakhan Shaheen E
doaj   +1 more source

Avaliação da microbiota intestinal e sua relação com parâmetros metabólicos em mulheres com obesidade mórbida [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2014Introdução: A microbiota intestinal refere-se aos micro-organismos que reside no trato ...
Beserra, Bruna Teles Soares
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