Results 1 to 10 of about 258,061 (147)
Host Epigenetics in Intracellular Pathogen Infections. [PDF]
Int J Mol Sci, 2020 Some intracellular pathogens are able to avoid the defense mechanisms contributing to host epigenetic modifications. These changes trigger alterations tothe chromatin structure and on the transcriptional level of genes involved in the pathogenesis of many bacterial diseases. In this way, pathogens manipulate the host cell for their own survival.
Fol M, Włodarczyk M, Druszczyńska M.
europepmc +4 more sources
Sequestration of host metabolism by an intracellular pathogen [PDF]
eLife, 2016 For intracellular pathogens, residence in a vacuole provides a shelter against cytosolic host defense to the cost of limited access to nutrients. The human pathogen Chlamydia trachomatis grows in a glycogen-rich vacuole.
Lena Gehre +8 more
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Annulate lamellae and intracellular pathogens [PDF]
Cellular Microbiology, 2021 Annulate lamellae (AL) have been observed many times over the years on electron micrographs of rapidly dividing cells, but little is known about these unusual organelles consisting of stacked sheets of endoplasmic reticulum-derived membranes with nuclear pore complexes (NPCs). Evidence is growing for a role of AL in viral infection.
Eymieux, Sébastien +4 more
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The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
Emerging Microbes and Infections, 2023 The coronavirus disease 2019 (COVID-19) has caused enormous health risks and global economic disruption. This disease is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Haiyun Yu +4 more
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Persistent intracellular pathogens [PDF]
FEMS Microbiology Reviews, 2012 Intracellular pathogens live and replicate either within endosomal compartments or in the cytosol of diverse host cells such as macrophages, dendritic cells, neutrophils, fibroblasts, epithelial or endothelial cells or erythrocytes. Examples not only include all viruses, which represent obligate intracellular pathogens in the strictest sense, but also ...
Dehio, C., Berry, C., Bartenschlager, R.
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Mycobacterium tuberculosis-macrophage interaction: Molecular updates
Frontiers in Cellular and Infection Microbiology, 2023 Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where it interacts with macrophages.
Haotian Bo +11 more
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Frontiers in Cellular and Infection Microbiology, 2022 Understanding of how intracellular pathogens survive in their host cells is important to improve management of their diseases. This has been fruitful for intracellular bacteria, but it is an understudied area in fungal pathogens.
Emmanuel J. Santiago-Burgos +4 more
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The intracellular pathogen concept [PDF]
Molecular Microbiology, 2019 AbstractThe intracellular pathogen concept classifies pathogenic microbes on the basis of their site of replication and dependence on host cells. This concept played a fundamental role in establishing the field of cellular microbiology, founded in part by Dr.
Arturo Casadevall, Ferric C. Fang
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Epidemiology of intracellular pathogens [PDF]
Clinical Microbiology and Infection, 1996 Epidemiologic studies of Chlamydia pneumoniae have been conducted throughout the world. A rate of antibody prevalence of approximately 50% has been found in adults, with small regional differences. We studied the antibody prevalence of C. pneumoniae in healthy persons and patients with acute respiratory infections in Japan.
Niki, Yoshito, Kishimoto, Toshio
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Frontiers in Cellular and Infection Microbiology, 2020 Acinetobacter baumannii is an important causative agent of nosocomial infections worldwide. The pathogen also readily acquires resistance to antibiotics, and pan-resistant strains have been reported. A.
Qing-Ming Qin +8 more
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