Results 31 to 40 of about 258,180 (266)
Microorganisms, 2021 Immune responses to intracellular pathogens depend largely upon the activation of T helper type 1-dependent mechanisms. The contribution of B cells to establishing protective immunity has long been underestimated.
Klara Kubelkova, Ales Macela
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Diagnostic methods for intracellular pathogens [PDF]
Clinical Microbiology and Infection, 1996 Diagnosis of infection with Chlamydia pneumoniae is difficult and the optimal diagnostic procedure has yet to be established. C. pneumoniae is more difficult to isolate in tissue culture than C. trachomatis. Attention must be paid to the site from which the specimen is taken, and all specimens should be processed within 24 h or stored at 4 C. Serologic
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Molecular motors hijacking by intracellular pathogens [PDF]
Cellular Microbiology, 2006 Cargoes are transported intracellularly along cytoskeletal tracks composed of actin or tubulin. Their movement involves the action of molecular motor proteins that generate directed movement along microtubules or actin filaments. The three classes of molecular motors--kinesins, dyneins and myosins--are involved in a multiplicity of biological movements
Henry, T., Gorvel, J.P., Meresse, S.
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Purification and proteomics of pathogen-modified vacuoles and membranes
Frontiers in Cellular and Infection Microbiology, 2015 Certain pathogenic bacteria adopt an intracellular lifestyle and proliferate in eukaryotic host cells. The intracellular niche protects the bacteria from cellular and humoral components of the mammalian immune system, and at the same time, allows the ...
Jo-Ana eHerweg +10 more
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Glycosylating Effectors of Legionella pneumophila: Finding the Sweet Spots for Host Cell Subversion
Biomolecules, 2022 Work over the past two decades clearly defined a significant role of glycosyltransferase effectors in the infection strategy of the Gram-negative, respiratory pathogen Legionella pneumophila.
Yury Belyi +2 more
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mBio, 2020 Chlamydia spp. productively infect mucosal epithelial cells of multiple anatomical sites, including the conjunctiva, lungs, gastrointestinal (GI) tract, and urogenital tract.
Sandra G. Morrison +5 more
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Cell-Penetrating Antimicrobial Peptides with Anti-Infective Activity against Intracellular Pathogens
Antibiotics, 2022 Cell-penetrating peptides (CPPs) are natural or engineered peptide sequences with the intrinsic ability to internalize into a diversity of cell types and simultaneously transport hydrophilic molecules and nanomaterials, of which the cellular uptake is ...
Gabriela Silva Cruz +3 more
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An intracellular bacterial pathogen triggers RIG-I/MDA5-dependent necroptosis
Current Research in Microbial SciencesRIG-I and MDA5 are members of RIG-I-like receptors (RLRs) that detect viral RNA within the cytoplasm and subsequently initiate antiviral immune responses.
Hang Xu, Huili Li, Boguang Sun, Li Sun
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mBioChlamydia trachomatis has adapted to subvert signaling in epithelial cells to ensure successful intracellular development. Interferon-γ (IFNγ) produced by recruited lymphocytes signals through the JAK/STAT pathway to restrict chlamydial growth in the ...
Francis L. Fontanilla +3 more
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mSphere, 2023 Coxiella burnetii is an intracellular bacterium that causes the human disease Q fever. C. burnetii forms a large, acidic Coxiella-containing vacuole (CCV) and uses a type 4B secretion system to secrete effector proteins into the host cell cytoplasm ...
Baleigh Schuler +2 more
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