Results 31 to 40 of about 334,616 (250)
Intracellular Transport in Cancer Metabolic Reprogramming
Frontiers in Cell and Developmental Biology, 2020 Tumor progression is a complex process consisting of several steps characterized by alterations in cellular behavior and morphology. These steps include uncontrolled cell division and proliferation, invasiveness and metastatic ability.
Marte Sneeggen +2 more
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Effect of the T-domain on intracellular transport of diphtheria toxin [PDF]
The Ukrainian Biochemical Journal, 2014 Subunit B of diphtheria toxin (DT), which consists of two domains: R (receptor-binding) and T (transmembrane), plays an important role in toxin-receptor binding on the cell-targets and in transportation of catalytic subunit A to the cell cytosol ...
А. J. Labyntsev +5 more
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Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]
, 1992 The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Johnson, Judith P. +3 more
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Virulence, 2021 It is now clear that the intercellular transport on microtubules by dynein and kinesin-1 motors has an important role in the replication and spread of many viruses.
Wei Hou +5 more
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An Update on the Interplay between LRRK2, Rab GTPases and Parkinson’s Disease
Biomolecules, 2023 Over the last decades, research on the pathobiology of neurodegenerative diseases has greatly evolved, revealing potential targets and mechanisms linked to their pathogenesis.
Tadayuki Komori, Tomoki Kuwahara
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Control of Spatially Heterogeneous and Time-Varying Cellular Reaction Networks: A New Summation Law [PDF]
, 2002 A hallmark of a plethora of intracellular signaling pathways is the spatial separation of activation and deactivation processes that potentially results in precipitous gradients of activated proteins. The classical Metabolic Control Analysis (MCA), which
Kholodenko, Boris N. +2 more
core +3 more sources
Myosin-Driven Intracellular Transport [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The delivery of intracellular material within cells is crucial for maintaining normal function. Myosins transport a wide variety of cargo, ranging from vesicles to ribonuclear protein particles (RNPs), in plants, fungi, and metazoa. The properties of a given myosin transporter are adapted to move on different actin filament tracks, either on the ...
openaire +2 more sources
Pharmaceutics, 2021 Lipid structures, such as liposomes or micelles, are of high interest as an approach to support the transport and delivery of active agents as a drug delivery system.
Claudia Claus +3 more
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Optical excitation and detection of neuronal activity [PDF]
, 2017 Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn, can modulate behavior in live organisms. However, detecting the response to the optical stimulation requires electrophysiology with physical contact or ...
Gillette, Martha +8 more
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Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
Nature Communications, 2017 Actin and microtubules play important roles in Golgi structure and function but how they are connected is poorly understood. Here the authors show that KIF20A is involved in the fission process and, in association with Myosin II, serves to anchor RAB6 on
Stéphanie Miserey-Lenkei +12 more
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