Results 11 to 20 of about 334,616 (250)
Intracellular transport driven by cytoskeletal motors: General mechanisms and defects
Physics Reports, 2015 Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large.
Appert-Rolland, Cecile +2 more
core +5 more sources
Managing intracellular transport [PDF]
Worm, 2013 Formation and normal function of neuronal synapses are intimately dependent on the delivery to and removal of biological materials from synapses by the intracellular transport machinery. Indeed, defects in intracellular transport contribute to the development and aggravation of neurodegenerative disorders.
Chua, J., Jahn, R., Klopfenstein, D.
openaire +3 more sources
Intracellular cholesterol transport [PDF]
Journal of Clinical Investigation, 2002 Cholesterol is the single most abundant lipid species in mammalian cells. More than 2×109 years of evolution designed this molecule to perfectly fit into phospholipid bilayers regulating the fluidity, permeability and bending stiffness of biological membranes.
Frederick R, Maxfield, Daniel, Wüstner
openaire +2 more sources
Intracellular transports and atherogenesis [PDF]
Frontiers in Bioscience, 2020 There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis. Among the many factors that influence this process, food plays a significant role.
Alexander A. Mirоnоv +4 more
openaire +3 more sources
Branched Actin Maintains Acetylated Microtubule Network in the Early Secretory Pathway
Cells, 2021 In the early secretory pathway, the delivery of anterograde cargoes from the endoplasmic reticulum (ER) exit sites (ERES) to the Golgi apparatus is a multi-step transport process occurring via the ER-Golgi intermediate compartment (IC, also called ERGIC).
Azumi Yoshimura +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Since cell nucleus is one of the most vulnerable compartments, the maximum therapeutic effect from a variety of locally acting agents, such as photosensitizers, alfa-emitters, Auger electron emitters, will be expected when they get there.
Tatiana S. Karyagina +9 more
doaj +1 more source
Chromothripsis—Explosion in Genetic Science
Cells, 2021 Chromothripsis has been defined as complex patterns of alternating genes copy number changes (normal, gain or loss) along the length of a chromosome or chromosome segment (International System for Human Cytogenomic Nomenclature 2020).
Mariia Shorokhova +2 more
doaj +1 more source
Cells, 2020 The synthetic polymer, polyallylamine hydrochloride (PAA), is found in a variety of applications in biotechnology and medicine. It is used in gene and siRNA transfer, to form microcapsules for targeted drug delivery to damaged and tumor cells ...
Larisa Alekseenko +6 more
doaj +1 more source
Coexistence and efficiency of normal and anomalous transport by molecular motors in living cells [PDF]
, 2013 Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells.
Goychuk, Igor +2 more
core +6 more sources
Pharmaceutics, 2023 A large number of proteins are successfully used to treat various diseases. These include natural polypeptide hormones, their synthetic analogues, antibodies, antibody mimetics, enzymes, and other drugs based on them.
Andrey A. Rosenkranz +1 more
doaj +1 more source