Results 61 to 70 of about 803,683 (201)

Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome

open access: yesFrontiers in Neuroscience, 2019
Fragile X syndrome (FXS) is a neurodevelopmental disorder that causes intellectual disability, as well as the leading monogenic cause of autism spectrum disorders (ASD), in which neurons show aberrant dendritic spine structure.
Ke Cheng   +20 more
doaj   +1 more source

A Tug-of-War Model Explains the Saltatory Sperm Cell Movement in Arabidopsis thaliana Pollen Tubes by Kinesins With Calponin Homology Domain

open access: yesFrontiers in Plant Science, 2021
Upon pollination, two sperm cells are transported inside the growing pollen tube toward the apex. One sperm cell fertilizes the egg cell to form the zygote, while the other fuses with the two polar nuclei to form the triploid endosperm.
Saskia Schattner   +5 more
doaj   +1 more source

Kinesin Light Chains Are Essential for Axonal Transport in Drosophila [PDF]

open access: yes, 1998
Kinesin is a heterotetramer composed of two 115-kD heavy chains and two 58-kD light chains. The microtubule motor activity of kinesin is performed by the heavy chains, but the functions of the light chains are poorly understood.
Beushausen, Sven   +4 more
core   +2 more sources

Intracellular Transport: Kinesins Working Together [PDF]

open access: yesCurrent Biology, 2008
While most in vitro experiments with motor proteins focus on the behavior of individual motors, in cells most cargo are transported by multiple motors and even multiple classes of motor. How these motors cooperate and compete in transporting cargo is not clear.
openaire   +2 more sources

Intracellular Metabolite Transporters in Plants [PDF]

open access: yesMolecular Plant, 2010
Due to the presence of plastids, eukaryotic photosynthetic cells represent the most highly compartmentalized eukaryotic cells. This high degree of compartmentation requires the transport of solutes across intracellular membrane systems by specific membrane transporters.
Linka, Nicole, Weber, Andreas P.M.
openaire   +2 more sources

Intracellular transport by active diffusion [PDF]

open access: yesTrends in Cell Biology, 2009
All substances exhibit constant random motion at the microscopic scale. This is a direct consequence of thermal agitation, and leads to diffusion of molecules and small particles in a liquid. In addition to this nondirected motion, living cells also use active transport mechanisms, such as motor activity and polymerization forces that depend on linear ...
Brangwynne, C. P.   +3 more
openaire   +3 more sources

HyPer as a tool to determine the reductive activity in cellular compartments

open access: yesRedox Biology
A multitude of cellular metabolic and regulatory processes rely on controlled thiol reduction and oxidation mechanisms. Due to our aerobic environment, research preferentially focuses on oxidation processes, leading to limited tools tailored for ...
Andrei Zhuravlev   +8 more
doaj   +1 more source

Particle interactions and lattice dynamics: Scenarios for efficient bidirectional stochastic transport?

open access: yes, 2011
Intracellular transport processes driven by molecular motors can be described by stochastic lattice models of self-driven particles. Here we focus on bidirectional transport models excluding the exchange of particles on the same track.
Alberts B   +11 more
core   +2 more sources

Cyclic AMP pathway activation and extracellular zinc induce rapid intracellular zinc mobilization in Candida albicans [PDF]

open access: yes, 2018
LK was supported by Innovation Fund Denmark, DK (4019-00019B). Pcovery ApS received funding from Wellcome Trust, Research Councils, UK (100480/Z/12), Novo Seeds, DK and Boehringer Ingelheim Venture Fund, D.
Anja T. Fuglsang   +4 more
core   +3 more sources

Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro

open access: yesAntibodies, 2013
Ricin is a type II ribosome inactivating protein (RIP) isolated from castor beans. Its high toxicity classifies it as a possible biological weapon. On the other hand, ricin linked to specific monoclonal antibodies or used in other conjugates has powerful
Monika Słomińska-Wojewódzka   +1 more
doaj   +1 more source

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