Results 21 to 30 of about 105,725 (272)

Intrahepatic Cholestasis Is a Clinically Significant Feature Associated with Natural History of X-Linked Myotubular Myopathy (XLMTM): A Case Series and Biopsy Report

Journal of Neuromuscular Diseases, 2021
X-linked myotubular myopathy (XLMTM) is a rare, life-threatening congenital myopathy characterized by profound skeletal muscle weakness, respiratory distress, and motor dysfunction.
C. Molera, Tinatin Sarishvili, A. Nascimento, I. Rtskhiladze, G. Muñoz Bartolo, S. Fernández Cebrián, Justo Valverde Fernández, B. Muñoz Cabello, R. Graham, W. Miller, B. Sepulveda, B. Kamath, H. Meng, M. Lawlor   +13 more
semanticscholar   +1 more source

Compound Heterozygous MYO5B Mutation, a Cause of Infantile Cholestasis: A Case Report

Journal of Nepal Medical Association, 2022
Infantile cholestasis is a common clinical problem in early infancy characterised by impairment in bile formation and/or flow. It requires prompt evaluation for underlying aetiology to initiate appropriate management.
Muna Khanal, Adarsh Kumar Jha, Arun Kumar Sharma   +2 more
doaj   +1 more source

Alterations of the Human Gut Microbiota in Intrahepatic Cholestasis of Pregnancy

Frontiers in Cellular and Infection Microbiology, 2021
Background and Aims Women with severe intrahepatic cholestasis of pregnancy (ICP) are at higher risks of fetal complications and without effective treatments.
Qitao Zhan, Xuchen Qi, R. Weng, Fangfang Xi, Yuan Chen, Yayun Wang, Wen-sheng Hu, Baihui Zhao, Q. Luo   +8 more
semanticscholar   +1 more source

Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases

Revista da Sociedade Brasileira de Medicina Tropical, 2021
Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/
Leonardo Rodrigues de Oliveira, Ana Laura Castro Costa, Paula Veloso Almeida, Luzia Beatriz Ribeiro Zago, Vanessa Afonso da Silva, Sheila Soares-Silva   +5 more
doaj   +1 more source

Intrahepatic cholestasis of pregnancy: risk factors for severe disease

Journal of Maternal-Fetal & Neonatal Medicine, 2021
Introduction Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-associated hepatic disorder characterized by pruritus in the setting of elevated serum bile acids (BA).
S. Mashburn, Ellen Schleckman, Paige Cackovic, Cynthia Shellhaas, K. Rood, M. Ma’ayeh   +5 more
semanticscholar   +1 more source

A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations [PDF]

, 2018
The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis.
Anapaz, V, Branco, J, Cardoso, M, Carvalho, R, Horta, D, Martins, A, Reis, J, Rodrigues, C   +7 more
core   +1 more source

Tectorigenin alleviates intrahepatic cholestasis by inhibiting hepatic inflammation and bile accumulation via activation of PPARγ

British Journal of Pharmacology, 2021
Increasing evidence suggests that human cholestasis is closely associated with the accumulation and activation of hepatic macrophages. Research indicates that activation of PPARγ exerts liver protective effects in cholestatic liver disease (CLD ...
Jiaqing Xiang, Guangyan Yang, Chuanrui Ma, Lingling Wei, Han Wu, Wei Zhang, X. Tao, Ling-yun Jiang, Zhen Liang, Lin Kang, Shu Yang   +10 more
semanticscholar   +1 more source

Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation

Case Reports in Obstetrics and Gynecology, 2021
Introduction. Benign recurrent intrahepatic cholestasis is a rare hepatologic disorder characterized by recurrent, self-limited episodes of severe pruritus, jaundice, and elevated bile acids.
Mariam Ayyash, Nicolina Smith, Madhurima Keerthy, Ashina Singh, Majid Shaman   +4 more
doaj   +1 more source

Liver Transplantation for Alagille's Syndrome [PDF]

, 1993
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J, Starzl, TE, Tepetes, K, Todo, S, Tzakis, AG, Tzoracoleftherakis, V   +5 more
core   +1 more source

Intrahepatic Cholestasis of Pregnancy: Natural History and Current Management

Seminars in liver disease (Print), 2021
Intrahepatic cholestasis of pregnancy (ICP) is a common disorder in the second half of pregnancy characterized by pruritus and elevated serum bile acids (BAs) with spontaneous resolution after delivery.
Rebecca Roediger, J. Fleckenstein
semanticscholar   +1 more source