Results 211 to 220 of about 57,277 (349)

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Intranasal delivery of engineered anti-SARS-CoV-2 extracellular vesicles therapeutically represses lung infection and inflammation. [PDF]

Drug Deliv Transl Res
Idris A, Idris A, Shrivastava S, Gao W, Supramaniam A, Tayyar Y, West NP, Kelly G, Acharya D, McMillan NAJ, Morris KV.   +10 more
europepmc   +1 more source

Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors [PDF]

, 2009
David Marks, Kristal R. Tucker, Melissa Ann Cavallin, Thomas G. Mast, Debra Ann Fadool   +4 more
openalex   +1 more source

Thermoreversible Gel Formulation for the Intranasal Delivery of Salmon Calcitonin and Comparison Studies of <i>In Vivo</i> Bioavailability

, 2022
Levent Alparslan, Gülbeyaz Yıldız Türkyılmaz, Leyla Didem Kozacı, Ercüment Karasulu   +3 more
openalex   +1 more source

Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer's Disease. [PDF]

Int J Nanomedicine
Sun C, Sha S, Shan Y, Gao X, Li L, Xing C, Guo Z, Du H.   +7 more
europepmc   +1 more source

The costs and benefits of a prison needle and syringe program in Australia, 2025–30: a modelling study

Medical Journal of Australia, Volume 222, Issue 8, Page 396-402, May 2025.
Abstract Objectives To estimate and compare the costs and benefits of introducing a prison needle and syringe program in all Australian prisons. Study design Stochastic compartmental modelling study. Setting All Australian prisons, 1 January 2010 to 31 December 2030.
Farah Houdroge, Samantha Colledge‐Frisby, Nadine Kronfli, Rebecca J Winter, Joanne Carson, Mark Stoove, Nick Scott   +6 more
wiley   +1 more source

Novel intranasal delivery of sihosogansan demonstrates rapid antidepressant activity via GABAergic and BDNF/TrkB pathways: identification of potential bioactive quality markers. [PDF]

Chin Med
Tran KN, Munni YA, Nguyen LTH, Oh TW, Choi HJ, Moon IS, Yang IJ.   +6 more
europepmc   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Cellulose‐Based Nanocomposites in Drug Delivery and Antimicrobial Therapies: Emerging Innovations and Translational Outlook

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Applications of cellulose‐based nanocomposites in antimicrobial drug delivery. ABSTRACT Cellulose‐based nanocomposites have emerged as sustainable and versatile biomaterials with promising applications in drug delivery and antimicrobial therapy.
Suraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Javedh Shareef   +4 more
wiley   +1 more source

Intranasal delivery of DPSC-derived small extracellular vesicles-encased phloroglucinol attenuates non-motor and motor deficits and promotes neurogenesis in an in vivo rat model of Parkinson's disease. [PDF]

Stem Cell Res Ther
Mondal K, Ghanty R, Mahadevan A, Waghmare G, Santhoshkumar R, Bn N, Datta I.   +6 more
europepmc   +1 more source