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Nanosystems for Intranasal Delivery of Therapeutics in Psychiatric Disorders
Current Drug DeliveryDue to the blood-brain barrier (BBB) and issues with oral and other traditional routes of administration, psychiatric disorders present significant challenges in getting therapeutics into the brain. The nose-to-brain pathway, also known as intranasal delivery, has shown promise in overcoming these barriers ...
Samin, Hamidi +2 more
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Intranasal drug delivery: opportunities and toxicologic challenges during drug development
Drug Delivery and Translational Research, 2021Olivia M Merkel, Andreas Popp
exaly
Navigating the challenges in pediatric intranasal drug delivery
Expert Opinion on Drug DeliveryPediatric intranasal (IN) drug delivery is a promising noninvasive way of administering medication, offering a significant improvement over parenteral and oral methods. However, its effectiveness is hindered by major technical challenges, primarily stemming from the wide anatomical variations among children and the difficulty in achieving consistent ...
Xiomara, Owen +2 more
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Intranasal insulin delivery and therapy.
Advanced drug delivery reviewsIntranasal insulin delivery has been widely investigated as an alternative to subcutaneous injection for the treatment of diabetes. The pharmacokinetic profile of intranasal insulin is similar to that obtained by intravenous injection and, in contrast to subcutaneous insulin delivery, bears close resemblance to the 'pulsatile' pattern of endogenous ...
, Hinchcliffe, , Illum
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Intranasal Delivery of Liposomes to Glioblastoma by Photostimulation of the Lymphatic System
Pharmaceutics, 2023Oxana Semyachkina-Glushkovskaya +2 more
exaly