Results 201 to 210 of about 31,838 (257)

Intranasal Delivery of Brain-Derived Neurotrophic Factor (BDNF)-Loaded Small Extracellular Vesicles for Treating Acute Spinal Cord Injury in Rats and Monkeys. [PDF]

J Extracell Vesicles
Huang Z, Li J, Wo J, Li CL, Wu ZC, Deng XH, Liang Y, Li F, Chen B, Jia B, Wang L, Wang Y, Sun G, Li Z, Zhu H, Guest JD, So KF, Fu QL, Zhou L.   +18 more
europepmc   +1 more source

Intranasal Delivery of Ketamine Induces Cortical Disinhibition. [PDF]

eNeuro
Qiao X, Grieco SF, Yu Z, Holmes TC, Xu X.   +4 more
europepmc   +1 more source

Nose to Brain: Exploring the Progress of Intranasal Delivery of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers. [PDF]

Int J Nanomedicine
Zheng Y, Cui L, Lu H, Liu Z, Zhai Z, Wang H, Shao L, Lu Z, Song X, Zhang Y.   +9 more
europepmc   +1 more source

Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case. [PDF]

J Neurosurg Case Lessons
Schönthal AH, Swenson S, Senecal FM, Mittenzwei R, Go JL, Chen TC.   +5 more
europepmc   +1 more source

Brain-targeted intranasal delivery of protein-based gene therapy for treatment of ischemic stroke. [PDF]

Theranostics
Ryu JY, Cerecedo-Lopez C, Yang H, Ryu I, Du R.   +4 more
europepmc   +1 more source

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Intranasal delivery of antipsychotic drugs

Schizophrenia Research, 2017
Antipsychotic drugs are used to treat psychotic disorders that afflict millions globally and cause tremendous emotional, economic and healthcare burdens. However, the potential of intranasal delivery to improve brain-specific targeting remains unrealized. In this article, we review the mechanisms and methods used for brain targeting via the intranasal (
Jayant Bhandari, Todd Hoare
exaly   +3 more sources

Intranasal delivery of biotechnology-based therapeutics

Drug Discovery Today, 2022
Biotechnology-based therapeutics include a wide range of products, such as recombinant hormones, stem cells, therapeutic enzymes, monoclonal antibodies, genes, vaccines, among others. The administration of these macromolecules has been studied via various routes.
Dhrumi, Patel, Bharvi, Patel, Sarika, Wairkar   +2 more
openaire   +2 more sources

Intranasal delivery: Physicochemical and therapeutic aspects

International Journal of Pharmaceutics, 2007
Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues to grow rapidly. The nasal mucosa offers numerous benefits as a target issue for drug delivery, such as a large surface area for delivery, rapid drug onset, potential for central nervous system delivery, and no first-pass metabolism.
L Illum, Paul H Johnson, Steven C Quay
exaly   +3 more sources