Results 101 to 110 of about 22,711 (279)

Safety Profile of Nebulized Ciprofloxacin‐Dexamethasone After Pediatric Airway Surgery

The Laryngoscope, EarlyView.
ABSTRACT Objective To evaluate the safety profile and patterns of use of nebulized ciprofloxacin–dexamethasone (CPD) in pediatric patients undergoing airway surgery. Methods A retrospective chart review was performed of patients who underwent airway surgery at a tertiary pediatric center between 2019 and 2023 and received nebulized CPD 0.3%–0.1 ...
Abbey L. Landini, Cyrus W. Abrahamson, Maya Frost, David Spielberg, Inbal Hazkani, Dana M. Thompson, Jonathan B. Ida, Sarah Maurrasse, Taher Valika   +8 more
wiley   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Intranasal Drug Delivery by Nanotechnology: Advances in and Challenges for Alzheimer's Disease Management. [PDF]

Pharmaceutics, 2023
Dighe S, Jog S, Momin M, Sawarkar S, Omri A.   +4 more
europepmc   +1 more source

Intranasal drug delivery: a novel approach [PDF]

Indian Journal of Otolaryngology and Head & Neck Surgery, 2009
Yashpal, Chugh, Pragati, Kapoor, A K, Kapoor   +2 more
openaire   +2 more sources

Hierarchical Porous Carbon—PLLA and PLGA Hybrid Nanoparticles for Intranasal Delivery of Galantamine for Alzheimer’s Disease Therapy

, 2020
In the present study, poly(l-lactic acid) (PLLA) and poly(lactide-co-glycolide) (PLGA) hybrid nanoparticles were developed for intranasal delivery of galantamine, a drug used in severe to moderate cases of Alzheimer’s disease. Galantamine (GAL) was
Georgios C. Papadopoulos, Chryssa Bekiari, Stavroula G. Nanaki, Pelagia Veneti, Niki Karouta, Ioannis Grivas, Dimitrios Gournis, Konstantinos Spyrou, Turki N. Baroud, Dimitrios N. Bikiaris   +9 more
core   +1 more source

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source

Research progress in brain-targeted nasal drug delivery

Frontiers in Aging Neuroscience
The unique anatomical and physiological connections between the nasal cavity and brain provide a pathway for bypassing the blood–brain barrier to allow for direct brain-targeted drug delivery through nasal administration.
Qingqing Huang, Qingqing Huang, Xin Chen, Sixun Yu, Gu Gong, Haifeng Shu, Haifeng Shu   +6 more
doaj   +1 more source

Tailorable Trimethyl chitosans as adjuvant for intranasal immunization

, 2010
Tailorable Trimethyl Chitosans as Adjuvant for Intranasal Immunization Active vaccination has proven to be the most (cost) effective tool in the fight against infectious diseases. Nowadays, most vaccines are administered via parenteral injection. However,
Pharmaceutics, Dep Farmaceutische wetenschappen, Verheul, R.J., Advanced drug delivery systems/drug targeting   +3 more
core  

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Navigating the Nose-to-Brain Route: A Systematic Review on Lipid-Based Nanocarriers for Central Nervous System Disorders

Pharmaceutics
Background: The blood–brain barrier (BBB) regulates brain substance entry, posing challenges for treating brain diseases. Traditional methods face limitations, leading to the exploration of non-invasive intranasal drug delivery.
Edoardo Agosti, Marco Zeppieri, Sara Antonietti, Luigi Battaglia, Tamara Ius, Caterina Gagliano, Marco Maria Fontanella, Pier Paolo Panciani   +7 more
doaj   +1 more source