Results 151 to 160 of about 22,711 (279)

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart, Lawrence Mbuagbaw, Joseph Beyene, Marwa Akola, Sarah Burrow, M. Constantine Samaan, Lehana Thabane, Adam Fleming, Donna L. Johnston, Shahrad R. Rassekh, Laura Banfield, Russell J. de Souza   +11 more
wiley   +1 more source

Towards an intranasal influenza vaccine based on whole inactivated influenza virus with N,N,N-trimethyl chitosan as adjuvant

, 2009
Vaccination provides the best form of protection against seasonal and pandemic influenza. Intranasal (i.n.) vaccination against influenza poses several advantages to an intramuscular injection, such as simple, noninvasive administration and the potential
Hagenaars, N., Dep Farmaceutische wetenschappen, Organon Farmaceutische Technologie, Advanced drug delivery systems/drug targeting   +3 more
core  

Safety and tolerance of oral ketamine: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Oral ketamine has gained increasing interest beyond anesthesia, particularly for treatment‐resistant depression, chronic pain, and pediatric procedural sedation. Despite expanding off‐label use, there is no standardized pharmaceutical formulation, and long‐term safety remains uncertain.
Nathalia Novaretti, Rebeca Mendes P. Pessoa, Jaime Eduardo Cecílio Hallak, Rafael Guimarães dos Santos, Marcos Hortes N. Chagas   +4 more
wiley   +1 more source

Nanoparticle-Based Combinational Strategies for Overcoming the Blood-Brain Barrier and Blood-Tumor Barrier

International Journal of Nanomedicine
Su Hyun Lim,1,2 Gi Taek Yee,3 Dongwoo Khang1,2,4 1Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon, 21999, South Korea; 2Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, 21999, South Korea; 3Department
Lim SH, Yee GT, Khang D
doaj  

Preparation and characterisation of PHT-loaded chitosan lecithin nanoparticles for intranasal drug delivery to the brain. [PDF]

RSC Adv, 2020
Yousfan A, Rubio N, Natouf AH, Daher A, Al-Kafry N, Venner K, Kafa H.   +6 more
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Mixed Amphiphilic Polymeric Nanoparticles of Chitosan, Poly(vinyl alcohol) and Poly(methyl methacrylate) for Intranasal Drug Delivery: A Preliminary In Vivo Study. [PDF]

Molecules, 2020
Schlachet I, Moshe Halamish H, Sosnik A.
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Brain delivery of small interfering ribonucleic acid and drugs through intranasal administration with nano-sized polymer micelles

Medical Devices: Evidence and Research, 2015
Takanori Kanazawa School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan Abstract: Recently, the development of effective strategies for enhancing drug delivery to the brain has been a topic of great interest in both clinical ...
Kanazawa T
doaj  

Novel Intranasal Drug Delivery: Geraniol Charged Polymeric Mixed Micelles for Targeting Cerebral Insult as a Result of Ischaemia/Reperfusion. [PDF]

Pharmaceutics, 2020
M Soliman S, M Sheta N, M M Ibrahim B, M El-Shawwa M, M Abd El-Halim S.   +4 more
europepmc   +1 more source