Results 131 to 140 of about 46,149 (284)

Pomegranate juice combined with inulin promote their mutual metabolic transformation by gut microbiota and prevent HFD-induced metabolic disorder in rats

Food Science and Human Wellness
High-fat diet (HFD) promotes the imbalance of gut microbiota, contributing to the development of metabolic disorders. Pomegranate juice (PJ) and inulin, as dietary polyphenol and dietary fiber respectively, have been reported to ameliorate diet-induced ...
Xiaoyu Song, Zhuoting Luo, Mengting Li, Jianke Li, Chen Hou   +4 more
doaj   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption

Scientific Reports
Inulin consumption and dihydrogen (H2) administration both exert antitumor effects on preclinical models as well as in clinical trials. As H2 is one of the major byproducts of inulin fermentation by bacterial species of the gut microbiota (GM), we ...
Victor Pascal-Moussellard, Jean-Pierre Alcaraz, Stéphane Tanguy, Cordélia Salomez-Ihl, Philippe Cinquin, François Boucher, Emilie Boucher   +6 more
doaj   +1 more source

Sugars as Central Integrators of Plant Immunity and Stress Responses

Plant, Cell &Environment, EarlyView.
ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło, Anna Barczak‐Brzyżek, Marcin Filipecki   +2 more
wiley   +1 more source

Prebiotic Bimuno® GOS reduces illness symptoms and supports gut barrier function and immunity after intermittent exercise in the heat

Experimental Physiology, EarlyView.
Abstract Exercise in hot climates increases the risk of gastrointestinal (GI) disruption and respiratory illness. We investigated the effects of a 42 day prebiotic intervention on markers of intestinal epithelial injury, GI discomfort and immunity following football specific exercise in the heat and daily upper respiratory illness.
Connor J. Parker, Samantha J. Abbott, Luke R. Butterfield, Kirsty A. Hunter, Michael A. Johnson, Graham R. Sharpe, Neil C. Williams   +6 more
wiley   +1 more source

Inulin and oligofructose: new scientific developments

, 2008
This article explores the potential role of inulin-type fructans in the human diet, focusing on scientific developments presented at the 5th Orafti Research Conference held at the Harvard Medical School in 2006, with special emphasis on the effects of ...
Delzenne, Nathalie M., Gibson, Glenn R.
core   +1 more source

Novel insoluble dye-labeled substrates for screening inulin-degrading microorganisms

, 2007
Inulin hydrogels were used to prepare insoluble colored substrates for screening of inulin-degrading microorganisms. Methycrylated inulin, synthesized with glycidyl methacrylate, was crossed-linked by free radical polymerization producing an insoluble ...
Im, WT, Ten, LN, Lee, Sung Taik, Larina, L, Aslam, Z   +4 more
core   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

Is the small intestinal epithelium truly "tight" to inulin permeation?

, 1991
In this study, we evaluated the "leakiness" of intestinal epithelium through examination of small intestinal absorption of inulin in vivo by perfusing rat jejunum with 10 microM inulin.
T. Y. Ma, R. A. Erickson, D. Hollander, P. Krugliak, H. Truong   +4 more
core   +1 more source