Kidney Structure and Blood Flow Predict Function and Enable Image‐Based eGFR With Non‐Contrast MRI
Multiparametric renal MRI in healthy adults identified cortical thickness (r² = 0.38) and renal blood flow (r² = 0.29; both p < 0.001) as the strongest predictors of creatinine‐based eGFR. Together, these measures explained 47% of eGFR variability. Prospective validation demonstrated low bias (−4.9 to 3.4 mL/min/1.73 m²) and good accuracy (p30: 87%–92%)
Emily Powell +5 more
wiley +1 more source
ABSTRACT Physiologically based pharmacokinetic (PBPK) models are increasingly used in pediatric drug development and matching such models to the target population is an important consideration. A US pediatric PBPK model was developed incorporating four sub‐groups describing physiology and enzymatic/transporter levels for White, African American ...
Trevor N. Johnson +5 more
wiley +1 more source
Dietary components shape the gut microbiome, which modifies bile acids through transformations. The resulting bile acid pool is sensed by host receptors to regulate immunity, metabolism, and intestinal function. Targeted bile acid measurements provide a unifying readout to study diet‐microbiome interactions and to develop next‐generation dietary ...
Jason Dichter
wiley +1 more source
Application of Chicory Root Inulin and Commercial Inulin in Various Food Products and Impact on Their Quality. [PDF]
Ostrun I +5 more
europepmc +1 more source
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source
Effects of Phosphorylated-Inulin Addition on the Technological Properties of Duck-Fat-Based Whipped Cream. [PDF]
Amjad MU +5 more
europepmc +1 more source
Designing Tissue Function Through Embedded Bioprinting Architectures
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li +4 more
wiley +1 more source
Effects of Different Types of Pectin Oligosaccharides on the Community Structure and Metabolism of Human Fecal Microbiota. [PDF]
Liu H, Geng X, Fu Y.
europepmc +1 more source
Sustainable levulinic acid production from inulin via hydrothermal conversion
Abstract This study investigates the hydrothermal conversion of inulin using potassium pyrosulfate to levulinic acid (LA). The Box–Behnken design approach was applied to optimize the conversion parameters and analyze the interactions influencing LA yield.
Gwi‐Taek Jeong
wiley +1 more source
Survival of Six Probiotic Strains During Simulated Gastrointestinal Digestion in Fermented Sheep's Milk Supplemented with Inulin and Sodium Butyrate. [PDF]
Szajnar K +3 more
europepmc +1 more source

